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Azidocillin: Difference between revisions

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Revision as of 11:47, 3 September 2011 editBogBot (talk | contribs)Bots53,132 edits populated new fields in {{drugbox}} and reordered per bot approval. Report errors and suggestions to User_talk:BogBot← Previous edit Latest revision as of 23:14, 29 January 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers174,387 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper 
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{{Short description|Chemical compound}}
{{unreferenced|date=June 2011}}
{{Drugbox {{Drugbox
| Verifiedfields = changed
| verifiedrevid = 443223758
| Watchedfields = changed
| verifiedrevid = 444222259
| IUPAC_name = 6--3,3-dimethyl-7-oxo-4-thia-1-azabicycloheptane-2-carboxylic acid | IUPAC_name = 6--3,3-dimethyl-7-oxo-4-thia-1-azabicycloheptane-2-carboxylic acid
| image = Azidocillin.png | image = Azidocillin.svg


<!--Clinical data--> <!--Clinical data-->
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status = | legal_status =
| routes_of_administration = | routes_of_administration = Oral, ], ]


<!--Pharmacokinetic data--> <!--Pharmacokinetic data-->
| bioavailability = | bioavailability = 57–64%
| protein_bound = | protein_bound =
| metabolism = | metabolism =
| elimination_half-life = | elimination_half-life = 0.6-1.1 hrs
| excretion = | excretion = 37–50% active substance in urine


<!--Identifiers--> <!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 17243-38-8 | CAS_number = 17243-38-8
| ATC_prefix = J01 | ATC_prefix = J01
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB08795 | DrugBank = DB08795
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2105907
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 16735689 | ChemSpiderID = 16735689
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<!--Chemical data--> <!--Chemical data-->
| C=16 | H=17 | N=5 | O=4 | S=1 | C=16 | H=17 | N=5 | O=4 | S=1
| molecular_weight = 375.40228
| smiles = O=C(O)2N3C(=O)(NC(=O)(\N==)c1ccccc1)3SC2(C)C | smiles = O=C(O)2N3C(=O)(NC(=O)(\N==)c1ccccc1)3SC2(C)C
| InChI = 1/C16H17N5O4S/c1-16(2)11(15(24)25)21-13(23)10(14(21)26-16)18-12(22)9(19-20-17)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,22)(H,24,25)/t9-,10-,11+,14-/m1/s1
| InChIKey = ODFHGIPNGIAMDK-NJBDSQKTBL
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C16H17N5O4S/c1-16(2)11(15(24)25)21-13(23)10(14(21)26-16)18-12(22)9(19-20-17)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,22)(H,24,25)/t9-,10-,11+,14-/m1/s1 | StdInChI = 1S/C16H17N5O4S/c1-16(2)11(15(24)25)21-13(23)10(14(21)26-16)18-12(22)9(19-20-17)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,22)(H,24,25)/t9-,10-,11+,14-/m1/s1
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| StdInChIKey = ODFHGIPNGIAMDK-NJBDSQKTSA-N | StdInChIKey = ODFHGIPNGIAMDK-NJBDSQKTSA-N
}} }}
'''Azidocillin''' is a type of ].<ref>{{cite journal | vauthors = Axelsson A, Jensen C, Melin O, Singer F, von Sydow C | title = Treatment of acute maxillary sinusitis. V. Amoxicillin azidocillin, phenylpropanolamine and pivampicillin | journal = Acta Oto-Laryngologica | volume = 91 | issue = 3–4 | pages = 313–8 | year = 1981 | pmid = 6894819 | doi = 10.3109/00016488109138513 }}</ref><ref>{{cite journal | vauthors = Bergan T, Sørensen G | title = Pharmacokinetics of azidocillin in healthy adults | journal = Arzneimittel-Forschung | volume = 30 | issue = 12 | pages = 2185–91 | year = 1980 | pmid = 6894241 }}</ref>
'''Azidocillin''' is a type of ].

== References ==
{{reflist}}


{{Cell wall disruptive antibiotics}} {{Cell wall disruptive antibiotics}}


]

]

{{antibiotic-stub}}

]
]

Latest revision as of 23:14, 29 January 2023

Chemical compound Pharmaceutical compound
Azidocillin
Clinical data
Routes of
administration
Oral, IV, IM
ATC code
Pharmacokinetic data
Bioavailability57–64%
Elimination half-life0.6-1.1 hrs
Excretion37–50% active substance in urine
Identifiers
IUPAC name
  • 6--3,3-dimethyl-7-oxo-4-thia-1-azabicycloheptane-2-carboxylic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.037.510 Edit this at Wikidata
Chemical and physical data
FormulaC16H17N5O4S
Molar mass375.40 g·mol
3D model (JSmol)
SMILES
  • O=C(O)2N3C(=O)(NC(=O)(\N==)c1ccccc1)3SC2(C)C
InChI
  • InChI=1S/C16H17N5O4S/c1-16(2)11(15(24)25)21-13(23)10(14(21)26-16)18-12(22)9(19-20-17)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,22)(H,24,25)/t9-,10-,11+,14-/m1/s1
  • Key:ODFHGIPNGIAMDK-NJBDSQKTSA-N
  (what is this?)  (verify)

Azidocillin is a type of penicillin.

References

  1. Axelsson A, Jensen C, Melin O, Singer F, von Sydow C (1981). "Treatment of acute maxillary sinusitis. V. Amoxicillin azidocillin, phenylpropanolamine and pivampicillin". Acta Oto-Laryngologica. 91 (3–4): 313–8. doi:10.3109/00016488109138513. PMID 6894819.
  2. Bergan T, Sørensen G (1980). "Pharmacokinetics of azidocillin in healthy adults". Arzneimittel-Forschung. 30 (12): 2185–91. PMID 6894241.
Antibacterials active on the cell wall and envelope (J01C-J01D)
β-lactams
(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases
)
Penicillins (Penams)
Narrow
spectrum
β-lactamase sensitive
(1st generation)
β-lactamase resistant
(2nd generation)
Extended
spectrum
Aminopenicillins (3rd generation)
Carboxypenicillins (4th generation)
Ureidopenicillins (4th generation)
Other
Carbapenems / Penems
Cephems
Cephalosporins
Cephamycins
Carbacephems
1st generation
2nd generation
3rd generation
4th generation
5th generation
Siderophore
Veterinary
Monobactams
β-lactamase inhibitors
Combinations
Polypeptides
Lipopeptides
Other
  • Inhibits PG elongation and crosslinking: Ramoplanin
Intracellular
Other
Categories:
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