| Revision as of 14:29, 17 November 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Saving copy of the {{drugbox}} taken from revid 456652821 of page Fosphenytoin for the Chem/Drugbox validation project (updated: 'DrugBank', 'ChEMBL').← Previous edit |
Latest revision as of 14:25, 29 January 2022 edit undo119.246.116.98 (talk)No edit summary |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Drugbox |
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{{drugbox |
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| verifiedrevid = 477001424 |
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| Verifiedfields = changed |
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| IUPAC_name = 2-Oxo-<small>L</small>-threo-hexono-1,4-lactone-2,3-enediol<br />''or''<br />(''R'')-3,4-dihydroxy-5-((''S'')- 1,2-dihydroxyethyl)furan-2(5''H'')-one |
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| verifiedrevid = 402134440 |
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| image = L-Ascorbic_acid.svg |
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| IUPAC_name = (2,5-dioxo-4,4-diphenyl-imidazolidin-1-yl)methoxyphosphonic acid |
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| width = 200px |
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| image = Fosphenytoin.svg |
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| image2 = Ascorbic-acid-from-xtal-1997-3D-balls.png |
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| width = 250 |
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| width2 = 200px |
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| image2 = Fosphenytoin3d.png |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| Drugs.com = {{drugs.com|MTM|vitamin_c}} |
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| tradename = Cerebyx |
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| licence_EU = <!-- EMEA requires brand name --> |
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| Drugs.com = {{drugs.com|monograph|cerebyx}} |
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| licence_US = <!-- FDA may use generic name --> |
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| MedlinePlus = a604036 |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = D |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| legal_status = Rx-only |
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| pregnancy_category = A |
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| routes_of_administration = ], ] |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = general public availability |
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| routes_of_administration = oral |
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<!--Pharmacokinetic data--> |
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<!--Pharmacokinetic data--> |
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| bioavailability = 100% (]) |
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| bioavailability = rapid & complete |
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| protein_bound = 95 to 99% |
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| protein_bound = negligible |
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| elimination_half-life = varies according to plasma concentration <!-- can be 30 min to weeks, depending on body stores --> |
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| metabolism = ] |
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| excretion = renal |
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| elimination_half-life = 15 minutes to convert to phenytoin |
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| excretion = ] (as phenytoin) |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 93390-81-9 |
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| CAS_number = 50-81-7 |
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| ATC_prefix = N03 |
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| ATC_prefix = A |
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| ATC_suffix = AB05 |
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| ATC_suffix = 11G |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| PubChem = 56339 |
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| ChEBI = 29073 |
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| PubChem = 5785 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = DB01320 |
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| DrugBank = DB00126 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 50839 |
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| ChemSpiderID = 10189562 |
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| NIAID_ChemDB = 002072 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = B4SF212641 |
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| UNII = PQ6CK8PD0R |
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| KEGG_Ref = {{keggcite|changed|kegg}} |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D07993 |
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| KEGG = D00018 |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = <!-- blanked - oldvalue: 919 --> |
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| ChEMBL = 196 |
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| C=16 | H=15 | N=2 | O=6 | P=1 |
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<!--Chemical data--> |
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| molecular_weight = 362.274 g/mol |
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| chemical_formula = |
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| smiles = O=C3N(C(=O)C(c1ccccc1)(c2ccccc2)N3)COP(=O)(O)O |
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| C=6 | H=7 | O=6 |
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| InChI = 1/C16H15N2O6P/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23/h1-10H,11H2,(H,17,20)(H2,21,22,23) |
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| molecular_weight = 176.12 g/] |
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| InChIKey = XWLUWCNOOVRFPX-UHFFFAOYAX |
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| smiles = C((1C(=C(C(=O)O1)O)O)O)O |
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| InChI = 1/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C16H15N2O6P/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23/h1-10H,11H2,(H,17,20)(H2,21,22,23) |
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| StdInChI = 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = XWLUWCNOOVRFPX-UHFFFAOYSA-N |
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| StdInChIKey = CIWBSHSKHKDKBQ-JLAZNSOCSA-N |
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| synonyms = <small>L</small>-ascorbic acid |
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| density = 1.694 |
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| melting_point = 190 |
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| boiling_point = 553 |
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}} |
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