2-Ethoxyethanol: Difference between revisions

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	{{chembox		{{chembox
			\|Verifiedfields = changed
	\| verifiedrevid = 456499332
			\|Watchedfields = changed
	\| Name = 2-Ethoxyethanol
			\|verifiedrevid = 477213258
	\| ImageFile = 2-Ethoxyethanol2.svg
			\|Name = 2-Ethoxyethanol
	\| ImageSize = 200px
			\|ImageFile = 2-Ethoxyethanol2.svg
	\| ImageName = 2-Ethoxyethanol
			\|ImageName = 2-Ethoxyethanol
	\| IUPACName = 2-ethoxyethanol
			\|PIN = 2-Ethoxyethanol
	\| OtherNames = Cellosolve<br />ethylene glycol ethyl ether<br />oxitol<br />Ethyl Cellosolve
			\|OtherNames = Cellosolve<br />ethylene glycol ethyl ether<br />oxitol<br />Ethyl Cellosolve<br/>EGEE
	\| Section1 = {{Chembox Identifiers
			\|Section1={{Chembox Identifiers
	\| DrugBank_Ref = {{drugbankcite\|correct\|drugbank}}
			\|DrugBank_Ref = {{drugbankcite\|correct\|drugbank}}
	\| DrugBank = DB02249
	\| ChEBI_Ref = {{ebicite\|correct\|EBI}}		\|DrugBank = DB02249
			\|ChEBI_Ref = {{ebicite\|correct\|EBI}}
	\| ChEBI = 46788		\|ChEBI = 46788
	\| KEGG_Ref = {{keggcite\|correct\|kegg}}		\|KEGG_Ref = {{keggcite\|correct\|kegg}}
	\| KEGG = C14687		\|KEGG = C14687
	\| PubChem =		\|PubChem = 8076
	\| ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}		\|ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}
	\| ChemSpiderID = 13836591		\|ChemSpiderID = 13836591
			\|EC_number = 203-804-1
	\| SMILES = CCOCCO
			\|UNNumber = 1171
	\| InChI = 1/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3
			\|Beilstein = 1098271
	\| InChIKey = ZNQVEEAIQZEUHB-UHFFFAOYAD
			\|Gmelin = 82142
	\| StdInChI_Ref = {{stdinchicite\|correct\|chemspider}}
			\|SMILES = CCOCCO
	\| StdInChI = 1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3
			\|InChI = 1/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3
	\| StdInChIKey_Ref = {{stdinchicite\|correct\|chemspider}}
	\| ~~StdInChIKey~~ = ZNQVEEAIQZEUHB-~~UHFFFAOYSA-N~~		\|InChIKey = ZNQVEEAIQZEUHB-UHFFFAOYAD
			\|StdInChI = 1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3
	\| ChEMBL_Ref = {{ebicite\|correct\|EBI}}
			\|StdInChIKey = ZNQVEEAIQZEUHB-UHFFFAOYSA-N
	\| ChEMBL = 119596
	\| ~~UNII_Ref~~ = {{~~fdacite~~\|correct\|~~FDA~~}}		\|ChEMBL_Ref = {{ebicite\|correct\|EBI}}
			\|ChEMBL = 119596
	\| UNII = IDK7C2HS09
	\| ~~CASNo_Ref~~ = {{~~cascite~~\|correct\|~~CAS~~}}		\|UNII_Ref = {{fdacite\|correct\|FDA}}
			\|UNII = IDK7C2HS09
	\| CASNo = 110-80-5
			\|CASNo_Ref = {{cascite\|correct\|CAS}}
	\| RTECS = KK8050000
			\|CASNo = 110-80-5
	}}
			\|RTECS = KK8050000
	\| Section2 = {{Chembox Properties
			}}
	\| C=4\|H=10\|O=2
			\|Section2={{Chembox Properties
	\| Appearance = clear liquid
			\|C=4 \| H=10 \| O=2
	\| Density = 0.930 g/cm<sup>3</sup>, liquid
			\|Appearance = clear liquid
	\| Solubility = miscible
			\|Odor = sweet, ]-like
	\| MeltingPtC = -70
			\|Density = 0.930 g/cm<sup>3</sup>, liquid
	\| BoilingPtC = 135
			\|Solubility = miscible
	\| Viscosity =
			\|MeltingPtC = -70
	}}
			\|BoilingPtC = 135
	\| Section7 = {{Chembox Hazards
			\|VaporPressure = 4 mmHg (20°C)<ref name=PGCH/>
	\| ExternalMSDS =
			}}
	\| MainHazards =
			\|Section7={{Chembox Hazards
	\| NFPA-H = 2
	\| NFPA-F = 2		\|NFPA-H = 2
	\| NFPA-R =		\|NFPA-F = 2
			\|NFPA-R =
	\| FlashPt = 44 °C
			\|FlashPtC = 44
	\| RPhrases = {{R10}}, {{R20/21/22}},<br />{{R60}}, {{R61}}
	\| ~~SPhrases~~ = {{~~S53~~}}, {{~~S45~~}}		\|GHSPictograms = {{GHS02}}{{GHS06}}{{GHS07}}{{GHS08}}
			\|GHSSignalWord = Danger
	}}
			\|HPhrases = {{H-phrases\|226\|302\|331\|360}}
	\| Section8 = {{Chembox Related
			\|PPhrases = {{P-phrases\|201\|202\|210\|233\|240\|241\|242\|243\|261\|264\|270\|271\|280\|281\|301+312\|303+361+353\|304+340\|308+313\|311\|321\|330\|370+378\|403+233\|403+235\|405\|501}}
	\| Function = ]s
			\|PEL = TWA 200 ppm (740 mg/m<sup>3</sup>) <ref name=PGCH>{{PGCH\|0258}}</ref>
	\| OtherFunctn = ]<br />]
			\|ExploLimits = 1.7%-15.6%<ref name=PGCH/>
	\| OtherCpds = ]
			\|IDLH = 500 ppm<ref name=PGCH/>
	}}
			\|REL = TWA 0.5 ppm (1.8 mg/m<sup>3</sup>) <ref name=PGCH/>
			\|LC50 = 2000 ppm (rat, 7 hr)<br/>1820 ppm (mouse, 7 hr)<ref name=IDLH>{{IDLH\|110805\|2-Ethoxyethanol}}</ref>
			\|LD50 = 2451 mg/kg (mouse, oral)<br/>2125 mg/kg (rat, oral)<ref name=IDLH/>
			\|LCLo = 3000 ppm (guinea pig, 24 hr)<ref name=IDLH/>
			}}
			\|Section8={{Chembox Related
			\|OtherFunction_label = ]s
			\|OtherFunction = ]<br />]
			\|OtherCompounds = ]
			}}
	}}		}}

	'''2-Ethoxyethanol''', also known by the trademark '''~~]''' or '''ethyl~~ cellosolve''', is a ] used widely in commercial and industrial applications. It is a clear, colorless, nearly odorless liquid that is miscible with water, ], ], ], and ].		'''2-Ethoxyethanol''', also known by the trademark '''Ethyl cellosolve''', is a ] used widely in commercial and industrial applications. It is a clear, colorless, nearly odorless liquid that is miscible with water, ], ], ], and ].<ref name="Concentrations1996">{{cite book\|author=National Research Council (U.S.). Subcommittee on Spacecraft Maximum Allowable Concentrations\|title=Spacecraft maximum allowable concentrations for selected airborne contaminants\|url=https://books.google.com/books?id=3VZRtLk--BAC&pg=PT210\|access-date=19 February 2012\|year=1996\|publisher=National Academies Press\|isbn=978-0-309-05478-2\|page=189}}</ref>

	2-Ethoxyethanol ~~can be~~ manufactured by the reaction of ] with ].		2-Ethoxyethanol is manufactured by the reaction of ] with ].

	As with other ]s, 2-ethoxyethanol has the useful property of being able to dissolve chemically diverse compounds. It will dissolve oils, resins, grease, waxes, ], and lacquers. This is an ideal property as a multi-purpose cleaner, and, therefore, 2-ethoxyethanol is used in products, such as varnish removers and degreasing solutions.		As with other ]s, 2-ethoxyethanol has the useful property of being able to dissolve chemically diverse compounds. It will dissolve oils, resins, grease, waxes, ], and lacquers.<ref name="Concentrations1996"/> This is an ideal property as a multi-purpose cleaner, and, therefore, 2-ethoxyethanol is used in products such as varnish removers and degreasing solutions.

	==References==		==References==
	{{Citation style\|date=September 2007}}
	<references/>		<references/>
	*''Merck Index'', 11th Edition, '''3707'''.

	==External links==		==External links==
			*{{cite web\|title=Chemical Sampling Information 2-Ethoxyethanol\|url=https://www.osha.gov/dts/chemicalsampling/data/CH_239200.html\|website=www.osha.gov\|access-date=4 August 2014\|archive-date=8 August 2014\|archive-url=https://web.archive.org/web/20140808051237/https://www.osha.gov/dts/chemicalsampling/data/CH_239200.html\|url-status=dead}}
	*
			*
	*

	{{DEFAULTSORT:Ethoxyethanol, 2-}}		{{DEFAULTSORT:Ethoxyethanol, 2-}}
	]		]
	]		]
			]

	]
	]
	]
	]
	]

Latest revision as of 23:53, 7 January 2025

2-Ethoxyethanol
Names

Preferred IUPAC name 2-Ethoxyethanol
Other names Cellosolve ethylene glycol ethyl ether oxitol Ethyl Cellosolve EGEE
Identifiers
CAS Number	110-80-5
3D model (JSmol)	Interactive image
Beilstein Reference	1098271
ChEBI	CHEBI:46788
ChEMBL	ChEMBL119596
ChemSpider	13836591
DrugBank	DB02249
ECHA InfoCard	100.003.459
EC Number	203-804-1
Gmelin Reference	82142
KEGG	C14687
PubChem CID	8076
RTECS number	KK8050000
UNII	IDK7C2HS09
UN number	1171
CompTox Dashboard (EPA)	DTXSID7024087
InChI InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3Key: ZNQVEEAIQZEUHB-UHFFFAOYSA-N InChI=1/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3Key: ZNQVEEAIQZEUHB-UHFFFAOYAD
SMILES CCOCCO
Properties
Chemical formula	C₄H₁₀O₂
Molar mass	90.122 g·mol
Appearance	clear liquid
Odor	sweet, ether-like
Density	0.930 g/cm, liquid
Melting point	−70 °C (−94 °F; 203 K)
Boiling point	135 °C (275 °F; 408 K)
Solubility in water	miscible
Vapor pressure	4 mmHg (20°C)
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H226, H302, H331, H360
Precautionary statements	P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P281, P301+P312, P303+P361+P353, P304+P340, P308+P313, P311, P321, P330, P370+P378, P403+P233, P403+P235, P405, P501
NFPA 704 (fire diamond)	2 2
Flash point	44 °C (111 °F; 317 K)
Explosive limits	1.7%-15.6%
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	2451 mg/kg (mouse, oral) 2125 mg/kg (rat, oral)
LC₅₀ (median concentration)	2000 ppm (rat, 7 hr) 1820 ppm (mouse, 7 hr)
LC_Lo (lowest published)	3000 ppm (guinea pig, 24 hr)
NIOSH (US health exposure limits):
PEL (Permissible)	TWA 200 ppm (740 mg/m)
REL (Recommended)	TWA 0.5 ppm (1.8 mg/m)
IDLH (Immediate danger)	500 ppm
Related compounds
Related ethers	2-Propoxyethanol 2-Butoxyethanol
Related compounds	Ethylene glycol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is ?) Infobox references

Chemical compound

2-Ethoxyethanol, also known by the trademark Ethyl cellosolve, is a solvent used widely in commercial and industrial applications. It is a clear, colorless, nearly odorless liquid that is miscible with water, ethanol, diethyl ether, acetone, and ethyl acetate.

2-Ethoxyethanol is manufactured by the reaction of ethylene oxide with ethanol.

As with other glycol ethers, 2-ethoxyethanol has the useful property of being able to dissolve chemically diverse compounds. It will dissolve oils, resins, grease, waxes, nitrocellulose, and lacquers. This is an ideal property as a multi-purpose cleaner, and, therefore, 2-ethoxyethanol is used in products such as varnish removers and degreasing solutions.

References

^ NIOSH Pocket Guide to Chemical Hazards. "#0258". National Institute for Occupational Safety and Health (NIOSH).
^ "2-Ethoxyethanol". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
^ National Research Council (U.S.). Subcommittee on Spacecraft Maximum Allowable Concentrations (1996). Spacecraft maximum allowable concentrations for selected airborne contaminants. National Academies Press. p. 189. ISBN 978-0-309-05478-2. Retrieved 19 February 2012.

External links

"Chemical Sampling Information 2-Ethoxyethanol". www.osha.gov. Archived from the original on 8 August 2014. Retrieved 4 August 2014.
CDC - NIOSH Pocket Guide to Chemical Hazards

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