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{{Short description|Protein-coding gene in the species Homo sapiens}}
{{multiple issues|
{{Infobox_gene}}
{{Underlinked|date=March 2014}}
'''Interferon alpha-inducible protein 27''' is a ] that in humans is encoded by the ''IFI27'' ].<ref name="pmid8358738">{{cite journal | vauthors = Rasmussen UB, Wolf C, Mattei MG, Chenard MP, Bellocq JP, Chambon P, Rio MC, Basset P | display-authors = 6 | title = Identification of a new interferon-alpha-inducible gene (p27) on human chromosome 14q32 and its expression in breast carcinoma | journal = Cancer Research | volume = 53 | issue = 17 | pages = 4096–101 | date = September 1993 | pmid = 8358738 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IFI27 interferon, alpha-inducible protein 27| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3429}}</ref>
{{Orphan|date=February 2009}}
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== References ==
{{PBB|geneid=3429}}
'''Interferon alpha-inducible protein 27''' is a ] that in humans is encoded by the ''IFI27'' ].<ref name="pmid8358738">{{cite journal | author = Rasmussen UB, Wolf C, Mattei MG, Chenard MP, Bellocq JP, Chambon P, Rio MC, Basset P | title = Identification of a new interferon-alpha-inducible gene (p27) on human chromosome 14q32 and its expression in breast carcinoma | journal = Cancer Res | volume = 53 | issue = 17 | pages = 4096–101 |date=Sep 1993 | pmid = 8358738 | pmc = | doi = }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IFI27 interferon, alpha-inducible protein 27| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3429| accessdate = }}</ref>

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==References==
{{reflist}} {{reflist}}


==Further reading== == Further reading ==
{{refbegin | 2}} {{refbegin|2}}
* {{cite journal | vauthors = Taulés M, Rius E, Talaya D, López-Girona A, Bachs O, Agell N | title = Calmodulin is essential for cyclin-dependent kinase 4 (Cdk4) activity and nuclear accumulation of cyclin D1-Cdk4 during G1 | journal = The Journal of Biological Chemistry | volume = 273 | issue = 50 | pages = 33279–86 | date = December 1998 | pmid = 9837900 | doi = 10.1074/jbc.273.50.33279 | doi-access = free }}
{{PBB_Further_reading
* {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = November 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
| citations =
* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | display-authors = 6 | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = March 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
*{{cite journal | author=Taulés M, Rius E, Talaya D, ''et al.'' |title=Calmodulin is essential for cyclin-dependent kinase 4 (Cdk4) activity and nuclear accumulation of cyclin D1-Cdk4 during G1. |journal=J. Biol. Chem. |volume=273 |issue= 50 |pages= 33279–86 |year= 1999 |pmid= 9837900 |doi=10.1074/jbc.273.50.33279 }}
*{{cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000 | pmc=310948 }} * {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Reports | volume = 1 | issue = 3 | pages = 287–92 | date = September 2000 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 }} * {{cite journal | vauthors = Martensen PM, Søgaard TM, Gjermandsen IM, Buttenschøn HN, Rossing AB, Bonnevie-Nielsen V, Rosada C, Simonsen JL, Justesen J | display-authors = 6 | title = The interferon alpha induced protein ISG12 is localized to the nuclear membrane | journal = European Journal of Biochemistry | volume = 268 | issue = 22 | pages = 5947–54 | date = November 2001 | pmid = 11722583 | doi = 10.1046/j.0014-2956.2001.02545.x | doi-access = free }}
*{{cite journal | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 | pmc=1083732 }} * {{cite journal | vauthors = Izmailova E, Bertley FM, Huang Q, Makori N, Miller CJ, Young RA, Aldovini A | title = HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages | journal = Nature Medicine | volume = 9 | issue = 2 | pages = 191–7 | date = February 2003 | pmid = 12539042 | doi = 10.1038/nm822 | s2cid = 26145639 }}
*{{cite journal | author=Martensen PM, Søgaard TM, Gjermandsen IM, ''et al.'' |title=The interferon alpha induced protein ISG12 is localized to the nuclear membrane. |journal=Eur. J. Biochem. |volume=268 |issue= 22 |pages= 5947–54 |year= 2001 |pmid= 11722583 |doi=10.1046/j.0014-2956.2001.02545.x }} * {{cite journal | vauthors = Smidt KC, Hansen LL, Søgaard TM, Petersen LK, Knudsen UB, Martensen PM | title = A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene | journal = Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | volume = 1638 | issue = 3 | pages = 227–34 | date = July 2003 | pmid = 12878323 | doi = 10.1016/s0925-4439(03)00087-5 | doi-access = }}
*
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Izmailova E, Bertley FM, Huang Q, ''et al.'' |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191–7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 }} * {{cite journal | vauthors = Parker N, Porter AC | title = Identification of a novel gene family that includes the interferon-inducible human genes 6-16 and ISG12 | journal = BMC Genomics | volume = 5 | issue = 1 | pages = 8 | date = January 2004 | pmid = 14728724 | pmc = 343271 | doi = 10.1186/1471-2164-5-8 | doi-access = free }}
*{{cite journal | author=Smidt KC, Hansen LL, Søgaard TM, ''et al.'' |title=A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene. |journal=Biochim. Biophys. Acta |volume=1638 |issue= 3 |pages= 227–34 |year= 2003 |pmid= 12878323 |doi= }} * {{cite journal | vauthors = Namciu SJ, Friedman RD, Marsden MD, Sarausad LM, Jasoni CL, Fournier RE | title = Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1 | journal = Mammalian Genome | volume = 15 | issue = 3 | pages = 162–78 | date = March 2004 | pmid = 15014966 | doi = 10.1007/s00335-003-2311-y | s2cid = 8594824 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }} * {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | display-authors = 6 | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = October 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
*{{cite journal | author=Taguchi T, Kato Y, Baba Y, ''et al.'' |title=Protein levels of p21, p27, cyclin E and Bax predict sensitivity to cisplatin and paclitaxel in head and neck squamous cell carcinomas. |journal=Oncol. Rep. |volume=11 |issue= 2 |pages= 421–6 |year= 2004 |pmid= 14719078 |doi= }} * {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | display-authors = 6 | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = January 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
*{{cite journal | author=Parker N, Porter AC |title=Identification of a novel gene family that includes the interferon-inducible human genes 6-16 and ISG12. |journal=BMC Genomics |volume=5 |pages= 8 |year= 2004 |pmid= 14728724 |doi= 10.1186/1471-2164-5-8 | pmc=343271 }} * {{cite journal | vauthors = Fjaerli HO, Bukholm G, Krog A, Skjaeret C, Holden M, Nakstad B | title = Whole blood gene expression in infants with respiratory syncytial virus bronchiolitis | journal = BMC Infectious Diseases | volume = 6 | pages = 175 | date = December 2006 | pmid = 17166282 | pmc = 1713240 | doi = 10.1186/1471-2334-6-175 | doi-access = free }}
*{{cite journal | author=Namciu SJ, Friedman RD, Marsden MD, ''et al.'' |title=Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1. |journal=Mamm. Genome |volume=15 |issue= 3 |pages= 162–78 |year= 2004 |pmid= 15014966 |doi= 10.1007/s00335-003-2311-y }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 | pmc=1347501 }}
*{{cite journal | author=Fjaerli HO, Bukholm G, Krog A, ''et al.'' |title=Whole blood gene expression in infants with respiratory syncytial virus bronchiolitis. |journal=BMC Infect. Dis. |volume=6|pages= 175 |year= 2007 |pmid= 17166282 |doi= 10.1186/1471-2334-6-175 | pmc=1713240 }}
}}
{{refend}} {{refend}}

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{{gene-14-stub}} {{gene-14-stub}}

Latest revision as of 23:43, 2 December 2023

Protein-coding gene in the species Homo sapiens
IFI27
Identifiers
AliasesIFI27, FAM14D, ISG12, ISG12A, P27, interferon alpha inducible protein 27
External IDsOMIM: 600009; HomoloGene: 128815; GeneCards: IFI27; OMA:IFI27 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)
Chromosome 14 (human)Genomic location for IFI27Genomic location for IFI27
Band14q32.12Start94,104,836 bp
End94,116,695 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lung

  • gallbladder

  • spleen

  • mucosa of transverse colon

  • apex of heart

  • upper lobe of left lung

  • right uterine tube

  • olfactory zone of nasal mucosa

  • subcutaneous adipose tissue

  • rectum
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

3429

n/a

Ensembl

ENSG00000165949
ENSG00000275214

n/a

UniProt

P40305

n/a

RefSeq (mRNA)
NM_005532
NM_001130080
NM_001288952
NM_001288954
NM_001288956

NM_001288957
NM_001288958
NM_001288959
NM_001288960
NM_001288995
NM_001366993
NM_001366994

n/a

RefSeq (protein)
NP_001123552
NP_001275881
NP_001275883
NP_001275885
NP_001275886

NP_001275887
NP_001275888
NP_001275889
NP_001275924
NP_005523
NP_001353922
NP_001353923

n/a

Location (UCSC)Chr 14: 94.1 – 94.12 Mbn/a
PubMed searchn/a
Wikidata
View/Edit Human

Interferon alpha-inducible protein 27 is a protein that in humans is encoded by the IFI27 gene.

References

  1. ^ ENSG00000275214 GRCh38: Ensembl release 89: ENSG00000165949, ENSG00000275214Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Rasmussen UB, Wolf C, Mattei MG, Chenard MP, Bellocq JP, Chambon P, et al. (September 1993). "Identification of a new interferon-alpha-inducible gene (p27) on human chromosome 14q32 and its expression in breast carcinoma". Cancer Research. 53 (17): 4096–101. PMID 8358738.
  4. "Entrez Gene: IFI27 interferon, alpha-inducible protein 27".

Further reading

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