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@] removed concerning the use of esketamine as a treatment for depression (as well as a reference to an FDA press release stating that it had been approved) and stated that I needed to obtain a secondary source and discuss this on the talkpage. Spravato is an FDA-approved intranasal formulation of esketamine with an indication for treatment resistant depression when combined with an oral antidepressant. I think that this is an important treatment modality that should be listed with other treatments for depression. There are many high-quality, WP:MEDRS complaint sources that are about the Spravato that are readily available. Examples of peer reviewed MEDRS sources include {{PMID|32729898}} and {{PMID|32163257}}. While on the topic of ketamine for depression, I feel that it could be worthwhile to discuss racemic ketamine as a treatment like the ] has, although this is not currently FDA approved for this indication. In closing, I feel there should be a mention of esketamine in the treatment section of the article and possibly also about ketamine in general. Thanks. ] (]) 00:38, 20 August 2022 (UTC)
@] removed concerning the use of esketamine as a treatment for depression (as well as a reference to an FDA press release stating that it had been approved) and stated that I needed to obtain a secondary source and discuss this on the talkpage. Spravato is an FDA-approved intranasal formulation of esketamine with an indication for treatment resistant depression when combined with an oral antidepressant. I think that this is an important treatment modality that should be listed with other treatments for depression. There are many high-quality, WP:MEDRS complaint sources that are about Spravato that are readily available. Examples of peer reviewed MEDRS sources include {{PMID|32729898}} and {{PMID|32163257}}. While on the topic of ketamine for depression, I feel that it could be worthwhile to discuss racemic ketamine as a treatment like the ] has, although this is not currently FDA approved for this indication. In closing, I feel there should be a mention of esketamine in the treatment section of the article and possibly also about ketamine in general. Thanks. ] (]) 00:38, 20 August 2022 (UTC)
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I have removed this content which was added directly to the lead, cited to a source that does not rise to the level of sourcing expected for a featured article; in fact, may not rise to the level WP:MEDRS prefers for even a non-featured article. The content a) should be cited to a recent, high-quality secondary review or textbook; b) should be added to the appropriate place in the body of the article rather than the lead, and c) is probably WP:UNDUE for the lead even if properly cited. MaryMO (AR) please have a look at WP:MEDRS, WP:WIAFA (which require high-quality sources), WP:LEAD (which explains that the lead is a summary of content in the body), and WP:FAOWN. SandyGeorgia (Talk) 21:04, 17 May 2022 (UTC)
Greetings @SandyGeorgia:. I'm concerned that this Misplaced Pages article includes little or no discussion of depression as a women's health issue, particularly in perimenopausal women. There's a passing mention of the higher incidence of depression in women, "Major depression is about twice as common in women as in men" (citation 2003) but little else. Given the current structure of the article, I'm not sure where to start. Do you have any suggestions as to what might be an appropriate place in the body of the article? Or examples of where this is handled well? Many thanks, MaryMO (AR) (talk) 15:51, 18 May 2022 (UTC)
Where to put the content depends on what the content is; for example, the FA on TS has a Tourette_syndrome#Pregnancy section under the Management section, because the secondary-sourced review literature covers management during pregnancy. See WP:MEDORDER for suggestions of what content goes where. Keep in mind that content for a featured article should be from high-quality secondary literature reviews or textbooks, that due weight should be taken into consideration (does information belong better in a sub article?), and the lead is not the place to introduce content that is not in the body of the article. It will be easier to help decide what content to put where if you first provide the high-quality sources you would like to reflect. SandyGeorgia (Talk) 21:17, 18 May 2022 (UTC)
The correctly formatted citation for this article is:
Gordon JL, Sander B (November 2021). "The role of estradiol fluctuation in the pathophysiology of perimenopausal depression: a hypothesis paper". Psychoneuroendocrinology (Review). 133: 105418. doi:10.1016/j.psyneuen.2021.105418. PMID34607269.
The correctly formatted citation for this article is:
Albert KM, Newhouse PA (May 2019). "Estrogen, stress, and depression: cognitive and biological interactions". Annu Rev Clin Psychol (Review). 15: 399–423. doi:10.1146/annurev-clinpsy-050718-095557. PMID30786242.
Guidelines from The North American Menopause Society (NAMS) and the National Network of Depression Centers Women and Mood Disorders Task Group (NNDC) ... WP:MEDRS calls for guidelines from national or international expert bodies ... has anyone ever heard of these groups ??? Depending on consensus as to whether these guidelines are in sync with better recognized international bodies, content may be usable. SandyGeorgia (Talk) 23:23, 19 May 2022 (UTC)
It is a review, but somewhat dated; whether it is usable depends on a search to make sure the information remains current. SandyGeorgia (Talk) 23:25, 19 May 2022 (UTC)
Psychosocial factors
Very little is said in the article about the psychosocial factors that may play a role in the development of a major depressive disorder. I hope somebody with more knowledge than me on the subject can improve the article with this info. --Savig (talk) 08:35, 15 June 2022 (UTC)
Other terms related to major depressive disorder/episodes.
I have found other terms related to major depressive disorder/episodes. I thought that they could be included in this article to increase the scope of MDD but somebody says that none of them belong here and that the article is already too long, even though there are articles that are even longer . The list of other terms are:
... section is getting stubby ... lots of short paragraphs and information that needs to be merged or possibly removed. I see student editing here. (Also found info chunked in to the lead that was nowhere in the body, so fixed that.) SandyGeorgia (Talk) 18:50, 17 August 2020 (UTC)
Elderly
This section looks also like it was chunked in as an afterthought. It duplicates some management information, which can be merged to Management or deleted, and the rest of it can go within the other sections as appropriate (prognosis or epidemiology?). SandyGeorgia (Talk) 19:08, 17 August 2020 (UTC)
Out of whack, and looks like people are just chunking in random factoids here, rather than following WP:WIAFA. "There has been a continuing discussion of whether neurological disorders and mood disorders may be linked to creativity," has WHAT to do with stigma? The section is not very well written. SandyGeorgia (Talk) 19:13, 17 August 2020 (UTC)
That section dates right back to the FAC. I can see it there almost unchanged in December 2008. So I think I might be the guilty party on that one. :P - I do think we need to do something about the length of the article and updating etc. Am looking now.Cas Liber (talk·contribs) 01:20, 18 August 2020 (UTC)
Resurrecting this from the archive, as this is now the longest standing medicine-related FA at Misplaced Pages:Featured article review/notices given. Sandy and Casliber, how do you feel about the article's current state? If you're pleased with changes, I can remove it from the template. If not, I can try to whip up some volunteers to plug away at any deficiencies. All else fails, we can start the WP:FAR process. Thanks for all your work on this! -- and of course thanks to Casliber for doing the heavy lifting to bring this to FA condition almost 13 years ago. I hope you're both doing well. Ajpolino (talk) 14:47, 8 August 2021 (UTC)
@Ajpolino: I think the article needs some cleanup. I've mostly been looking at unclear/inelegant prose today, but I intend look into Sandy's content concerns soon. Haven't gotten through the whole article yet, but the "Pathophysiology" section, for one, seems overly detailed. Cheers, Ovinus (talk) 00:39, 25 September 2021 (UTC)
What I'm doing is comparing the current version to this which was soon after it was promoted and near time it was mainpaged. Just to compare the prose and scope mainly. However, the data needs to be updated to latest studies. I've begun adjusting the prose a bit. Work in progress....Cas Liber (talk·contribs) 14:16, 25 September 2021 (UTC)
Basic Problems of this Article
Hi, I was studying this article that I realized there were many sentences that do not have a reference. Also, the references were not added to the article alike, some one are sfn and others are not. Many parts need to be updated and the article is not comprehensive. I do not know how this article was Featured but must not be Featured now. Pereoptic09:29, 13 August 2022 (UTC)
I can't find a single unsourced paragraph in this entire article, are they any concrete instances you can point out where a source would be needed but is lacking? I ask the same for what you think needs updating and what information is missing.--Megaman en m (talk) 11:21, 13 August 2022 (UTC)
Likewise, where is the specific uncited text? Every sentence does not need to be cited; the reference may after a subsequent sentence. SandyGeorgia (Talk) 15:42, 13 August 2022 (UTC)
@Megaman en m:For example, the first paragraph of the management section, the second paragraph of Antidepressants.
@SandyGeorgia: The main problems I mentioned in the article were not the only one. To the things I mentioned above, add the short introduction of the article and Having a reference in the introduction.
Issues not covered in the article: , In the pathophysiology section, it is also possible to discuss the relationship between major depression and chronic diseases
The first paragraph of management clearly references the NICE guidelines, which are cited at the end of that para (including the bullet points). The second paragraph of antidepressants is cited, so I'm unsure if I'm looking somewhere different than you are ?? The size of the lead is fine, and citations in the lead are neither required nor discouraged; I see no problem there. Could you please provide a PMID or description of what you consider not covered, so others don't have to click on each little bracketed number to see the concern? It would help, thanks. Casliber I am wearying of being the only person maintaining this article. Can we get it updated or else move to the next step? I am swamped, and yet here I am, trying to click on little numbers to figure out what is wanted next. SandyGeorgia (Talk) 20:51, 13 August 2022 (UTC)
Joyous it is not, and I'm really tired of it; we need committed FA-knowledgeable editors to keep this article updated. Are the 2004 NICE guidelines the latest? SandyGeorgia (Talk) 21:53, 13 August 2022 (UTC)
This reference to ==> Cause and Prognosis (for example generalized anxiety disorder, obsessive-compulsive disorder, panic disorder, and social anxiety disorder and poor treatment outcomes)
I think this reference is considered a secondary review, because at the end of it, the bibliography section is placed. In addition, its source is the American Psychiatric Association. Pereoptic13:09, 14 August 2022 (UTC)
I'm not using a source like that in a Featured article; an alternate approach to adding whatever content you wish to include is to see if any of the sources listed at the end of that article are secondary reviews, and use them. SandyGeorgia (Talk) 15:09, 14 August 2022 (UTC)
I will mention the shortcomings of the article's introduction in the future. My written English grammar is a little weak, otherwise I would have added the required content to the article myself. Pereoptic09:27, 14 August 2022 (UTC)
I'm willing to help do the updates as I have time, but I can get to things faster if you provide MEDRS sources and if I don't have to do all the citation formatting (see above). Do you have the tool for citing PMIDs used in this article? Or you can use the PMID template followed by a bracket and the number for easier reference. For today, I have to finish work on another Featured article, so perhaps someone else will get to them faster. Spicy have you any interest in helping maintain this FA? I don't have time to get to it today, and two updates needed are identified above. SandyGeorgia (Talk) 11:45, 14 August 2022 (UTC)
Laishley EJ, Barrett AM, Isaac O, Thiemer K, Jariwalla R, Grossberg SE, Sedmak JJ, Anderson TR, Slotkin TA (November 1975). "Regulation and properties of an invertase from Clostridium pasteurianum". Can J Microbiol. 21 (11): 1711–8. doi:10.1139/m75-251. PMID140. to ==> CausePereoptic13:22, 14 August 2022 (UTC)
Better :) I can attempt to work on some of this over time, but for the next few days, I am up to my eyeballs at the Joan of ArcFeatured article review, and must stay focused on getting that wrapped up. I'm hoping someone else will jump in here to help ... what is listed so far does not look insurmountable. SandyGeorgia (Talk) 18:54, 14 August 2022 (UTC)
I hope you will be successful in improving the above article. There is no rush, we will improve the article as time permits. I will also try to add things to the article over time, although it needs to be checked grammatically by an English speaker. Sincerely Pereoptic20:28, 14 August 2022 (UTC)
Urgent FAR needed
I am one person and cannot maintain this old FA alone, and will no longer endure the demoralization of trying to do so. This is one of the oldest listed at WP:FARGIVEN, and my recommendation is that someone submit it urgently to WP:FAR. SandyGeorgia (Talk) 14:36, 18 August 2022 (UTC)
Esketamine as treatment for MDD
@SandyGeorgia removed my edits concerning the use of esketamine as a treatment for depression (as well as a reference to an FDA press release stating that it had been approved) and stated that I needed to obtain a secondary source and discuss this on the talkpage. Spravato is an FDA-approved intranasal formulation of esketamine with an indication for treatment resistant depression when combined with an oral antidepressant. I think that this is an important treatment modality that should be listed with other treatments for depression. There are many high-quality, WP:MEDRS complaint sources that are about Spravato that are readily available. Examples of peer reviewed MEDRS sources include PMID32729898 and PMID32163257. While on the topic of ketamine for depression, I feel that it could be worthwhile to discuss racemic ketamine as a treatment like the management of depression has, although this is not currently FDA approved for this indication. In closing, I feel there should be a mention of esketamine in the treatment section of the article and possibly also about ketamine in general. Thanks. Wikipedialuva (talk) 00:38, 20 August 2022 (UTC)
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