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Revision as of 20:47, 24 July 2023

Chemical compound
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Find sources: "Pramiconazole" – news · newspapers · books · scholar · JSTOR (January 2021) (Learn how and when to remove this message)
Pharmaceutical compound
Pramiconazole
Clinical data
Routes of
administration		By mouth
ATC code
  • none
Identifiers
IUPAC name
  • 1-{4-methoxy}phenyl)piperazin-1-yl]phenyl}-3-isopropylimidazolidin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC35H39F2N7O4
Molar mass659.725 g·mol
3D model (JSmol)
SMILES
  • CC(C)N1CCN(C1=O)c2ccc(cc2)N3CCN(CC3)c4ccc(cc4)OC5OC(O5)(Cn6cncn6)c7ccc(cc7F)F
InChI
  • InChI=1S/C35H39F2N7O4/c1-25(2)43-17-18-44(34(43)45)29-6-4-27(5-7-29)40-13-15-41(16-14-40)28-8-10-30(11-9-28)46-20-33-47-22-35(48-33,21-42-24-38-23-39-42)31-12-3-26(36)19-32(31)37/h3-12,19,23-25,33H,13-18,20-22H2,1-2H3/t33-,35+/m0/s1
  • Key:AEKNYBWUEYNWMJ-QWOOXDRHSA-N
  (what is this?)  (verify)

Pramiconazole is a triazole antifungal which was under development by Barrier Therapeutics for the treatment of acute skin and mucosal fungal infections but was never marketed.

References

  1. "Pramiconazole - AdisInsight".
  2. Geria AN, Scheinfeld NS (September 2008). "Pramiconazole, a triazole compound for the treatment of fungal infections". IDrugs: The Investigational Drugs Journal. 11 (9): 661–70. PMID 18763217.
Antifungals (D01 and J02)
Wall/
membrane
Ergosterol
inhibitors
Azoles (lanosterol 14α-
demethylase inhibitors)
Imidazoles
  • Systemic: ketoconazole
Triazoles
Thiazoles
Polyene antimycotics
(ergosterol binding)
Squalene monooxygenase
inhibitors
Allylamines
Benzylamines
Others
β-glucan synthase
inhibitors
Intracellular
Pyrimidine analogues/
thymidylate synthase inhibitors
Mitotic inhibitors
Aminoacyl tRNA synthetase inhibitors
Others


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