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Revision as of 20:04, 30 December 2024 editIshiura (talk | contribs)Extended confirmed users2,590 edits Created page with '{{Family name hatnote|Koyama|lang=Japanese}}{{Infobox officeholder | name = Koyama Shisei | image = | caption = | native_name = 小山 肆成 | native_name_lang = ja | birth_name = | birth_date = 1807 | birth_place = Hisagi Village, Kii Province, Japan | death_date = {{Death date and age|1862|10|28|1807}} | death_place = Kyoto, Yamashiro Province, Japan |...'  Revision as of 20:09, 30 December 2024 edit undoIshiura (talk | contribs)Extended confirmed users2,590 editsNo edit summaryNext edit →
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During the ] period (1830-1844), ] ravaged his native Kii Province. After Koyama learned that his nephew's entire family had died of smallpox in 1835, he immersed himself in research to discover a way to combat the disease.<ref name=manabi/> During the ] period (1830-1844), ] ravaged his native Kii Province. After Koyama learned that his nephew's entire family had died of smallpox in 1835, he immersed himself in research to discover a way to combat the disease.<ref name=manabi/>


At the beginning of the 19th century, the ] introduced ]'s technique of using ] to inoculate patients against smallpox to ]. Hearing of this, Koyama obtained from Takagai Ki'en a copy of the Chinese book ''Yin dou lue'' (引痘略), written by ] (丘熺) or Qiu Huochuan (邱活川), which contained an explanation of Jennerian inoculation.<ref name=manabi/> At the beginning of the 19th century, the ] introduced ]'s technique of using ] to inoculate patients against smallpox to ]. Hearing of this, Koyama obtained from Takagai Ki'en a copy of the Chinese book ''Yin dou lue'' (引痘略), written by ] (丘熺) or Qiu Huochuan (邱活川), which contained an explanation of Jennerian inoculation.<ref name=manabi/> Shisei's activites are primarily responsible for this information becoming widely available in Japan.<ref>{{cite journal |last1=Trambaiolo |first1=Daniel |title=Vaccination and the Politics of Medical Knowledge in Nineteenth-Century Japan |journal=Bulletin of the History of Medicine |date=2014 |volume=88 |issue=3 |publisher=Johns Hopkins University Press |location=United States}}</ref>


In 1849, Koyama successfully tested Japan's first Jennerian smallpox vaccine, {{Nihongo|Gyūkajintōbyō|牛化人痘苗}}, which allowed for a significantly higher chance of immunization than the European original. In 1849, Koyama successfully tested Japan's first Jennerian smallpox vaccine, {{Nihongo|Gyūkajintōbyō|牛化人痘苗}}, which allowed for a significantly higher chance of immunization than the European original.

Revision as of 20:09, 30 December 2024

In this Japanese name, the surname is Koyama.
Koyama Shisei
小山 肆成
Personal details
Born1807
Hisagi Village, Kii Province, Japan
DiedOctober 28, 1862(1862-10-28) (aged 54–55)
Kyoto, Yamashiro Province, Japan

Koyama Shisei (Japanese: 小山 肆成, 1807-1862) was a Japanese physician and vaccinologist. He also used the name Hōshū (蓬洲).

Koyama's reputation was such that he was compared with other outstanding scientists of his time, as in the phrase, "Seishū of the north, Hōshū of the south" (北の青洲、南の蓬洲).

Biography

He was born in 1807 near Hisagi (久木) village in rural Kii Province. When he was young, he traveled to Kyoto to study with his elder brother Koyama Fumiaki (小山 文明), but Fumiaki died suddenly in 1822. In 1823, he began studying Confucianism under his brother's teacher Okada Nangai (岡田 南涯), and medical science under Takagai Ki'en (高階 枳園), a physician to the Imperial Court. He also studied herbal medicine. Eventually, Koyama opened his own medical practice on Karasuma Street.

During the Tenpō period (1830-1844), smallpox ravaged his native Kii Province. After Koyama learned that his nephew's entire family had died of smallpox in 1835, he immersed himself in research to discover a way to combat the disease.

At the beginning of the 19th century, the Balmis Expedition introduced Edward Jenner's technique of using cowpox to inoculate patients against smallpox to Qing China. Hearing of this, Koyama obtained from Takagai Ki'en a copy of the Chinese book Yin dou lue (引痘略), written by Qiu Xi (丘熺) or Qiu Huochuan (邱活川), which contained an explanation of Jennerian inoculation. Shisei's activites are primarily responsible for this information becoming widely available in Japan.

In 1849, Koyama successfully tested Japan's first Jennerian smallpox vaccine, Gyūkajintōbyō (牛化人痘苗), which allowed for a significantly higher chance of immunization than the European original.

Koyama died in Kyoto in 1867.

See also

References

  1. ^ "小山肆成と羽山大学" (PDF). 和歌山県教育センター Wakayama Prefecture Education Center. Retrieved 30 December 2024.
  2. Trambaiolo, Daniel (2014). "Vaccination and the Politics of Medical Knowledge in Nineteenth-Century Japan". Bulletin of the History of Medicine. 88 (3). United States: Johns Hopkins University Press.
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