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Drug may refer to:
- medicine or other substance with pharmacological uses or potency, from Dutch droog = "dry" (ref. dried medicinal plants).
- any drug used for purposes perceived as recreational: see drug of abuse and recreational drug use.
- from use of drugs as sedatives, metaphoric word uses such as "drug on the market" = "something that people are unwilling to buy".
- any drug or demon in ancient Vedic Hinduism, from the Vedic Sanskrit root druh = "be hostile".
- the Drûg or Drúedain, a race of Men from Middle-earth in the fiction of J. R. R. Tolkien.
- sometimes used colloquially in the USA as past tense and past participle of the verb drag. (The correct form is "dragged".)
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