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| '''Martin J. Cline''' (born ]) is a ] at the ]. He is notable for being the first (in ]) to successfully transfer a functioning ] into a living ], creating the first ] organism. For this, he was censured by the ] ], which was funding his work. His research also describes the molecular genetic alterations in ], especially ]. | '''Martin J. Cline''' (born ]) is a ] at the ]. He is notable for being the first (in ]) to successfully transfer a functioning ] into a living ], creating the first ] organism. For this, he was censured by the ] ], which was funding his work. His research also describes the molecular genetic alterations in ], especially ]. | ||
| First unapproved/unauthorized attempt at gene therapy – In 1980, Dr. Martin Cline conducted a rDNA transfer into the bone marrow cells of two patients with hereditary blood disorders. . He did so in direct opposition to National Institute of Health gene therapy guidelines and without the approval of the Institutional Review Board at the University of California Los Angeles (UCLA), where his research was conducted. The ethical concerns that were generated prompted a call for review by a number of organizations – including the National Council of Churches, Synagogue Council of America, and the United States Catholic Conference. Consequently, Dr. Cline was forced to resign his department chairmanship at UCLA and lost several research grants. http://www.family.org/cforum/fosi/bioethics/genetics/a0032608.cfm | |||
| {{biologist-stub}} | {{biologist-stub}} | ||
Revision as of 15:05, 2 February 2006
Martin J. Cline (born 1934) is a geneticist at the University of California, Los Angeles. He is notable for being the first (in 1980) to successfully transfer a functioning gene into a living mouse, creating the first transgenic organism. For this, he was censured by the US National Institutes of Health, which was funding his work. His research also describes the molecular genetic alterations in cancer, especially leukemia.
First unapproved/unauthorized attempt at gene therapy – In 1980, Dr. Martin Cline conducted a rDNA transfer into the bone marrow cells of two patients with hereditary blood disorders. . He did so in direct opposition to National Institute of Health gene therapy guidelines and without the approval of the Institutional Review Board at the University of California Los Angeles (UCLA), where his research was conducted. The ethical concerns that were generated prompted a call for review by a number of organizations – including the National Council of Churches, Synagogue Council of America, and the United States Catholic Conference. Consequently, Dr. Cline was forced to resign his department chairmanship at UCLA and lost several research grants. http://www.family.org/cforum/fosi/bioethics/genetics/a0032608.cfm
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