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Iodophenpropit: Difference between revisions

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Revision as of 23:07, 1 March 2010 editحسن علي البط (talk | contribs)Extended confirmed users, Pending changes reviewers19,940 editsm Removed category Organic iodides; Quick-adding category Organoiodides (using HotCat)← Previous edit Revision as of 23:23, 5 December 2010 edit undoRjwilmsi (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers932,196 editsm formatting journal PMID cites using AWB (7434)Next edit →
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'''Iodophenpropit''' is a ] which binds selectively to the ] subtype. Its <sup>125</sup>I ] form is used for mapping the distribution of H<sub>3</sub> receptors in the body.<ref>Jansen FP, Wu TS, Voss HP, Steinbusch HW, Vollinga RC, Rademaker B, Bast A, Timmerman H. Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, -iodophenpropit, to rat brain. ''British Journal of Pharmacology''. 1994 Oct;113(2):355-62. PMID 7834183</ref><ref>Jansen FP, Mochizuki T, Maeyama K, Leurs R, Timmerman H. Characterization of histamine H3 receptors in mouse brain using the H3 antagonist iodophenpropit. ''Naunyn Schmiedebergs Archives of Pharmacology''. 2000 Jul;362(1):60-7. PMID 10935534</ref> '''Iodophenpropit''' is a ] which binds selectively to the ] subtype. Its <sup>125</sup>I ] form is used for mapping the distribution of H<sub>3</sub> receptors in the body.<ref>{{cite journal | pmid = 7834183 }}</ref><ref>{{cite journal | pmid = 10935534 }}</ref>


==References== ==References==

Revision as of 23:23, 5 December 2010

Iodophenpropit
Names
IUPAC name 3-(1H-imidazol-5-yl)propyl N'-imidothiocarbamate
Other names 1--N'-formamidine
Identifiers
CAS Number
3D model (JSmol)
MeSH Iodophenpropit
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • C1=CC(=CC=C1CCN=C(N)SCCCC2=CN=CN2)I
Properties
Chemical formula C15H19IN4S
Molar mass 414.30763
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Iodophenpropit is a histamine antagonist which binds selectively to the H3 subtype. Its I radiolabelled form is used for mapping the distribution of H3 receptors in the body.

References

  1. . PMID 7834183. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
  2. . PMID 10935534. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
Histamine receptor modulators
H1
Agonists
Antagonists
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
See also
Receptor/signaling modulators
Monoamine metabolism modulators
Monoamine reuptake inhibitors


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