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Sincalide: Difference between revisions

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Revision as of 08:07, 19 January 2011 editPashihiko (talk | contribs)Extended confirmed users3,563 editsNo edit summary← Previous edit Revision as of 16:17, 1 February 2011 edit undoLouisajb (talk | contribs)Extended confirmed users4,402 edits added chemblidNext edit →
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| PubChem = 32800 | PubChem = 32800
| DrugBank = | DrugBank =
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1121
| KEGG = D05845 | KEGG = D05845
| C=49|H=62|N=10|O=16|S=3 | C=49|H=62|N=10|O=16|S=3

Revision as of 16:17, 1 February 2011

Pharmaceutical compound
Sincalide
Clinical data
Other names1-De(5-oxo-L-proline)-2-de-L-glutamine-
5-L-methioninecaerulein, 3--3-(4-sulfooxyphenyl)propanoyl]amino]-4-
methylsulfanyl-butanoyl]amino]acetyl]amino]-3-
(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl-
butanoyl]amino]-3-propanoic acid
Routes of
administration
Intravenous
ATC code
Legal status
Legal status
  • US: ℞-only
  • Available on a named-patient basis (UK)
Identifiers
IUPAC name
  • α-aspartyl-O-sulfotyrosylmethionylglycyltryptophylmethionyl-α-aspartylphenylalaninamide
CAS Number
PubChem CID
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.042.384 Edit this at Wikidata
Chemical and physical data
FormulaC49H62N10O16S3
Molar mass1143.27 g/mol g·mol

Sincalide (INN) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin, and also known as CCK-8.

Common adverse effects following administration include abdominal discomfort and nausea. These effects are more pronounced following rapid infusion.

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Diagnostic agents (V04)
Digestive system
Diabetes
Fat absorption
Bile duct patency
Liver functional capacity
Gastric secretion
Exocrine pancreatic function
Endocrine system
Pituitary function
Thyroid function
Fertility disturbances
Tuberculosis
Renal function
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