Terconazole: Difference between revisions

Revision as of 04:19, 31 December 2011 editWhere next Columbus? (talk \| contribs)Extended confirmed users1,265 editsm →References: navbox Template:Antifungals ← Previous edit		Revision as of 19:50, 12 January 2012 edit undoCheMoBot (talk \| contribs)Bots141,565 edits Updating {{drugbox}} (changes to verified fields - added verified revid - updated 'ChEBI_Ref') per Chem/Drugbox validation (report errors or bugs)Next edit →
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	{{Drugbox		{{Drugbox
	\| Verifiedfields = changed		\| Verifiedfields = changed
	\| verifiedrevid = ~~411404554~~		\| verifiedrevid = 470602308
	\| IUPAC_name = 1-methoxy]phenyl]- 4-propan-2-yl-piperazine		\| IUPAC_name = 1-methoxy]phenyl]- 4-propan-2-yl-piperazine
	\| image = Terconazole.png		\| image = Terconazole.png
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	\| ATC_supplemental =		\| ATC_supplemental =
	\| PubChem = 441383		\| PubChem = 441383
	\| DrugBank_Ref = {{drugbankcite\|~~correct~~\|drugbank}}		\| DrugBank_Ref = {{drugbankcite\|changed\|drugbank}}
	\| DrugBank = APRD00659		\| DrugBank = APRD00659
	\| ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}		\| ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}
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	\| UNII_Ref = {{fdacite\|correct\|FDA}}		\| UNII_Ref = {{fdacite\|correct\|FDA}}
	\| UNII = 0KJ2VE664U		\| UNII = 0KJ2VE664U
	\| KEGG_Ref = {{keggcite\|~~changed~~\|kegg}}		\| KEGG_Ref = {{keggcite\|correct\|kegg}}
	\| KEGG = D00888		\| KEGG = D00888
	\| ChEMBL_Ref = {{ebicite\|correct\|EBI}}		\| ChEMBL_Ref = {{ebicite\|correct\|EBI}}

Revision as of 19:50, 12 January 2012

Pharmaceutical compound

Terconazole
Clinical data

Trade names	Terazol
AHFS/Drugs.com	Monograph
MedlinePlus	a688022
ATC code	G01AG02 (WHO)
Pharmacokinetic data
Protein binding	94.9%
Identifiers
IUPAC name 1-methoxy]phenyl]- 4-propan-2-yl-piperazine
CAS Number	67915-31-5
PubChem CID	441383
DrugBank	APRD00659
ChemSpider	390122
UNII	0KJ2VE664U
KEGG	D00888
ChEMBL	ChEMBL1306
CompTox Dashboard (EPA)	DTXSID2045498
ECHA InfoCard	100.061.573
Chemical and physical data
Formula	C₂₆H₃₁Cl₂N₅O₃
Molar mass	532.462 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES Clc1ccc(c(Cl)c1)4(O(COc3ccc(N2CCN(C(C)C)CC2)cc3)CO4)Cn5ncnc5
InChI InChI=1S/C26H31Cl2N5O3/c1-19(2)31-9-11-32(12-10-31)21-4-6-22(7-5-21)34-14-23-15-35-26(36-23,16-33-18-29-17-30-33)24-8-3-20(27)13-25(24)28/h3-8,13,17-19,23H,9-12,14-16H2,1-2H3/t23-,26-/m0/s1 Key:BLSQLHNBWJLIBQ-OZXSUGGESA-N
(what is this?) (verify)

Terconazole is an anti-fungal medication, primarily used to treat vaginal fungal infections.

Arsenic compounds

Quinoline derivatives

Imidazoles	Metronidazole Clotrimazole Miconazole Econazole Ornidazole Isoconazole Tioconazole Ketoconazole Fenticonazole Azanidazole Propenidazole Butoconazole Omoconazole Oxiconazole Flutrimazole
Triazoles	Terconazole
Polyenes	Nystatin Natamycin Amphotericin B
Other	Ciclopirox Methylrosaniline

Other

Wall/
membrane

Ergosterol
inhibitors

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine
Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	Systemic: flucytosine
Mitotic inhibitors	Systemic: griseofulvin
Aminoacyl tRNA synthetase inhibitors	Topical: tavaborole

Others

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