Revision as of 11:05, 17 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Saving copy of the {{chembox}} taken from revid 464126328 of page Alpha-Melanocyte-stimulating_hormone for the Chem/Drugbox validation project (updated: 'ChEMBL', 'CASNo').← Previous edit |
Revision as of 11:06, 17 February 2012 edit undoBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Saving copy of the {{drugbox}} taken from revid 460347387 of page Alpharadin for the Chem/Drugbox validation project (updated: 'CAS_number').Next edit → |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Chembox |
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{{Drugbox |
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| Verifiedfields = changed |
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| ImageFile = |
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| verifiedrevid = 458777866 |
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| ImageSize = |
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| name = Alpharadin |
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| IUPACName = ''N''-acetyl-<small>L</small>-seryl-<small>L</small>-tyrosyl-<small>L</small>-seryl-<small>L</small>-methionyl-<small>L</small>-α-glutamyl-<small>L</small>-histidyl-<small>D</small>-phenylalanyl-<small>L</small>-arginyl-<small>L</small>-tryptophylglycyl-<small>L</small>-lysyl-<small>L</small>-prolyl-<small>L</small>-valinamide |
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| IUPAC_name = Radium-223 chloride |
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| OtherNames = Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH<sub>2</sub> |
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| image = |
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| Section1 = {{Chembox Identifiers |
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| alt = |
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| CASNo = <!-- blanked - oldvalue: 581-05-5 --> |
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| caption = |
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| ChEMBL = 385886 |
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| PubChem = 16132636 |
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<!--Clinical data--> |
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| ChemSpiderID = 17289286 |
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| SMILES = |
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| tradename = |
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| Drugs.com = |
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| InChI = 1/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83) |
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| MedlinePlus = |
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| InChIKey = WHNFPRLDDSXQCL-UHFFFAOYAP |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| StdInChI = 1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83) |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| StdInChIKey = WHNFPRLDDSXQCL-UHFFFAOYSA-N |
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| pregnancy_category= |
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}} |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| Section2 = {{Chembox Properties |
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| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| Formula = C<sub>77</sub>H<sub>109</sub>N<sub>21</sub>O<sub>19</sub>S |
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| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM --> |
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| MolarMass = 1664.884 g/mol |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| Appearance = |
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| legal_status = Experimental |
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| MeltingPt = |
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| BoilingPt = |
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<!--Pharmacokinetic data--> |
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}} |
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| protein_bound = |
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| Section3 = {{Chembox Hazards |
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| metabolism = |
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}} |
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<!--Identifiers--> |
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| Section5 = {{Chembox Pharmacology |
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| CAS_number_Ref = {{cascite|changed|??}} |
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| HalfLife = 20 minutes<ref name="pmid20545686">{{cite journal | author = Langan EA, Nie Z, Rhodes LE | title = Melanotropic peptides: more than just 'Barbie drugs' and 'sun-tan jabs'? | journal = The British Journal of Dermatology | volume = 163 | issue = 3 | pages = 451–5 | year = 2010 | month = September | pmid = 20545686 | doi = 10.1111/j.1365-2133.2010.09891.x | url = http://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-0963&date=2010&volume=163&issue=3&spage=451}}</ref> |
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| CAS_number = <!-- blanked - oldvalue: 444811-40-9 --> |
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}} |
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| ATCvet = |
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| ATC_prefix = <!-- 'none' if uncategorised --> |
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| ATC_suffix = |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = RJ00KV3VTG |
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| PubChem = |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID = NA |
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<!--Chemical data--> |
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| chemical_formula = <sup>223</sup>RaCl<sub>2</sub> |
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| molecular_weight = 296.91 g/mol |
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}} |
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}} |