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Revision as of 13:01, 17 March 2013

Neuromedin N
Identifiers
CAS Number
3D model (JSmol)
IUPHAR/BPS
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • OC((CC(C)C)NC(((CC)C)()NC((CC1=CC=C(O)C=C1)NC(2CCCN2C((NC((N)CCCCN)=O)()(CC)C)=O)=O)=O)=O)=O
Properties
Chemical formula C38H63N7O8
Molar mass 745.949
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound
Neuromedin N
Identifiers
SymbolNN
NCBI gene4922
HGNC8038
Other data
LocusChr. 12 q21

Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.

References

  1. Neuromedin N - Compound Summary, PubChem.
  2. Carraway RE, Mitra SP, Spaulding G (1992). "Posttranslational processing of the neurotensin/neuromedin-N precursor". Annals of the New York Academy of Sciences. 668 (1 The Neurobiol): 1–16. doi:10.1111/j.1749-6632.1992.tb27335.x. PMID 1463268.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. Kitabgi P, De Nadai F, Rovère C, Bidard JN (1992). "Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N". Annals of the New York Academy of Sciences. 668 (1 The Neurobiol): 30–42. doi:10.1111/j.1749-6632.1992.tb27337.x. PMID 1463273.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. Vincent JP (1995). "Neurotensin receptors: binding properties, transduction pathways, and structure". Cellular and Molecular Neurobiology. 15 (5): 501–12. doi:10.1007/BF02071313. PMID 8719037. {{cite journal}}: Unknown parameter |month= ignored (help)
  5. Adams DH, Hanson GR, Keefe KA (2001). "Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum". Neuroscience. 102 (4): 843–51. doi:10.1016/S0306-4522(00)00530-3. PMID 11182247.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (2002). "Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity". Biochemical and Biophysical Research Communications. 290 (4): 1161–8. doi:10.1006/bbrc.2001.6308. PMID 11811984. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  7. Kitabgi P (2006). "Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases". Peptides. 27 (10): 2508–14. doi:10.1016/j.peptides.2006.03.038. PMID 16904237. {{cite journal}}: Unknown parameter |month= ignored (help)
Peptides: neuropeptides
Hormonessee hormones
Opioid peptides
Dynorphins
Endomorphins
Endorphins
Enkephalins
Others
Other
neuropeptides
Kinins
Bradykinins
Tachykinins: mammal
amphibian
Neuromedins
Orexins
Other

Template:Neuropeptidergics

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