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| He is perhaps best known for his work on ], a controversial ], which he was convinced had a palliative effect on certain mice tumors.<ref name=Hutchison1980>{{cite journal |author=Hutchison DJ |title=Kanematsu Sugiura 1890-1979 |journal=Cancer Res. |volume=40 |issue=7 |pages=2625–6 |year=1980 |month=July |pmid=6992988 |doi= |url=http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=6992988}}</ref> | He is perhaps best known for his work on ], a controversial ], which he was convinced had a palliative effect on certain mice tumors.<ref name=Hutchison1980>{{cite journal |author=Hutchison DJ |title=Kanematsu Sugiura 1890-1979 |journal=Cancer Res. |volume=40 |issue=7 |pages=2625–6 |year=1980 |month=July |pmid=6992988 |doi= |url=http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=6992988}}</ref> | ||
| == Accolades == | |||
| Kanematsu Sugiura was recognized by both the United | |||
| States and Japanese governments and scientific groups. For | |||
| his early research in radiation, Dr. Sugiura received a Leonard | |||
| Prize from the Roentgen Society in 1925. He was honored by | |||
| the Japanese government in 1960 for cultural services, and in | |||
| the same year Emperor Hirohito awarded him membership in | |||
| the Order of the Sacred Treasure, third class. He was cited by | |||
| Tokohu University, Kanazawa University, and Niigata University | |||
| for cultural services. In 1965, the Japan Medical Association | |||
| presented Dr. Sugiura with its highest award for outstanding | |||
| contributions to cancer research and for his services and | |||
| inspiration to so many Japanese physicians and surgeons. In | |||
| 1966, the mayor of New York City and the New York County | |||
| Medical Society recognized Dr. Sugiura for his cultural services | |||
| and for his dedication to the field of medicine. | |||
| <ref name=Obituary>{{cite journal |author=Cancer Research |title=Kanematsu Sugiura 1890-1979 |http://cancerres.aacrjournals.org/content/40/7/2625.full.pdf}}</ref> | |||
| == Laetrile controversy == | == Laetrile controversy == | ||
Revision as of 00:11, 31 December 2013
Kanematsu Sugiura (1890 – October 21, 1979 in White Plains, New York) was a cancer researcher who spent his career at the Memorial Sloan-Kettering Cancer Center. A pioneer in cancer research", he completed over 250 papers before his death. Sugiura received a number of awards and prizes throughout his life, and retired from the center in 1962.
He is perhaps best known for his work on laetrile, a controversial alternative cancer treatment, which he was convinced had a palliative effect on certain mice tumors.
Laetrile controversy
In 1972, Memorial Sloan-Kettering Cancer Center board member Benno Schmidt convinced the hospital to test laetrile in order to assert its ineffectiveness "with some conviction". Sugiura found that laetrile inhibited secondary tumors in mice, without destroying the primary tumor, but in a blind test was unable to conclude that laetrile had anticancer activity.
The initial positive results were not published because, in the words of Chester Stock, Sugiura's supervisor, it would have caused all kind of havoc. Nevertheless, they were leaked in 1973, causing a stir. Consequently laetrile was tested on 14 tumor systems, and a Sloan-Kettering press release concluded that laetrile showed no beneficial effects.
Three other researchers were unable to confirm Sugiura's results. Mistakes in the Sloan-Kettering press release were highlighted by a group of laetrile proponents, led by Ralph Moss, former public affairs official of Sloan-Kettering hospital, who was fired when he announced his membership in the group. These mistakes were considered inconsequential, but Nicholas Wade in Science noted that even the appearance of a departure from strict objectivity is unfortunate.
The results of all of the studies were published together in the Journal of Surgical Oncology.
References
- ^ Hutchison DJ (1980). "Kanematsu Sugiura 1890-1979". Cancer Res. 40 (7): 2625–6. PMID 6992988.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Wade N (1977). "Laetrile at Sloan-Kettering: A Question of Ambiguity". Science. 198 (4323): 1231–1234. doi:10.1126/science.198.4323.1231. PMID 17741690.
{{cite journal}}: Unknown parameter|month=ignored (help) - Published in Journal of Surgical Oncology 10(2).