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Brown tumors may be rarely associated with ectopic parathyroid adenomas.<ref>{{cite journal|last=Sharma|first=Ravi|author2=Mathan Mohan|author3=R S Neelakandan|author4=D Siddharth|title=An unusual case of brown tumor of hyperparathyroidism associated with ectopic parathyroid adenoma|journal=European Journal of Dentistry|date=October 2013|volume=7|issue=4|pages=500–503|doi=10.4103/1305-7456.120657|url=http://www.eurjdent.com/text.asp?2013/7/4/500/120657|accessdate=2013-10-28}}</ref>
Brown tumors may be rarely associated with ectopic parathyroid adenomas.<ref>{{cite journal|last=Sharma|first=Ravi|author2=Mathan Mohan|author3=R S Neelakandan|author4=D Siddharth|title=An unusual case of brown tumor of hyperparathyroidism associated with ectopic parathyroid adenoma|journal=European Journal of Dentistry|date=October 2013|volume=7|issue=4|pages=500–503|doi=10.4103/1305-7456.120657|url=http://www.eurjdent.com/text.asp?2013/7/4/500/120657|accessdate=2013-10-28}}</ref>
==Epidemiology==
Lesions are common in both the genders and become more vulnerable with age. However, it may be noted that hyperparathyroidism with bone disease has become rare as there is increased use of screening laboratory examinations. In the less developed nations, there may be still many patients with hyperparathyroidism and other advanced bone diseases. <ref>http://www.bonetumor.org/tumors-disorder-metabolism/brown-tumor</ref>
==See also==
==See also==
Revision as of 03:33, 14 January 2015
Medical condition
Brown tumor
The brown tumor is a bone lesion that arises in settings of excess osteoclast activity, such as hyperparathyroidism. It is not a true neoplasm, as the term "tumor" suggests; however, it may mimic a true neoplasm. Brown tumours are radiolucent on x-ray.
Brown tumours consist of fibrous tissue, woven bone and supporting vasculature, but no matrix. The osteoclasts consume the trabecular bone that osteoblasts lay down and this front of reparative bone deposition followed by additional resorption can expand beyond the usual shape of the bone, involving the periosteum thus causing bone pain. The characteristic brown coloration results from hemosiderin deposition into the osteolytic cysts. Hemosiderin deposition is not a distinctive feature of brown tumors; it may also be seen giant cell tumors of the bone.
Brown tumors may be rarely associated with ectopic parathyroid adenomas.
Epidemiology
Lesions are common in both the genders and become more vulnerable with age. However, it may be noted that hyperparathyroidism with bone disease has become rare as there is increased use of screening laboratory examinations. In the less developed nations, there may be still many patients with hyperparathyroidism and other advanced bone diseases.
