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Revision as of 16:52, 16 July 2021 editJJMC89 bot III (talk | contribs)Bots, Administrators3,684,692 editsm Moving Category:Heterocyclic compounds (2 rings) to Category:Heterocyclic compounds with 2 rings per Misplaced Pages:Categories for discussion/Log/2021 June 24#Category:Heterocyclic compounds (1 ring)← Previous edit Latest revision as of 16:09, 18 August 2022 edit undoFswitzer4 (talk | contribs)Extended confirmed users10,572 editsm Added UNII 
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| CASNo_Ref = {{cascite|changed|ChemSpider}} | CASNo_Ref = {{cascite|changed|ChemSpider}}
| CASNo = 369376-61-4 | CASNo = 369376-61-4
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = A69767WW45
| ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 450490 | ChEMBL = 450490

Latest revision as of 16:09, 18 August 2022

Pterulone
Names
Preferred IUPAC name 1-ethan-1-one
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
InChI
  • InChI=1S/C13H11ClO2/c1-9(15)11-4-5-13-12(6-11)3-2-10(7-14)8-16-13/h2-7H,8H2,1H3/b10-7-Key: QEWSARCWWQPUSM-YFHOEESVSA-N
  • InChI=1S/C13H11ClO2/c1-9(15)11-4-5-13-12(6-11)3-2-10(7-14)8-16-13/h2-7H,8H2,1H3/b10-7-
  • InChI=1S/C13H11ClO2/c1-9(15)11-4-5-13-12(6-11)3-2-10(7-14)8-16-13/h2-7H,8H2,1H3/b10-7-Key: QEWSARCWWQPUSM-YFHOEESVSA-N
SMILES
  • O=C(c2ccc1OCC(/C=C\c1c2)=Cl)C
Properties
Chemical formula C13H11ClO2
Molar mass 234.678
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Pterulone is a fungal metabolite. It was initially isolated from the mycelium and liquid cultures of wood-decay fungus in the genus Pterula. The compound inhibits eukaryotic respiration by targeting the mitochondrial NADH:ubiquinone oxidoreductase.

References

  1. Engler M, Anke T, Sterner O, Brandt U (1997). "Pterulinic acid and pterulone, two novel inhibitors of NADH:ubiquinone oxidoreductase (complex I) produced by a Pterula species. I. Production, isolation and biological activities". Journal of Antibiotics. 50 (4): 325–9. doi:10.7164/antibiotics.50.325. PMID 9186558.


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