Tetroxoprim: Difference between revisions

Revision as of 19:43, 9 January 2023 editOzzie10aaaa (talk \| contribs)Autopatrolled, Extended confirmed users, New page reviewers214,346 edits no need← Previous edit		Latest revision as of 20:29, 29 January 2023 edit undoEntranced98 (talk \| contribs)Extended confirmed users, Pending changes reviewers, Rollbackers174,416 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper
Line 1:		Line 1:
			{{Short description\|Chemical compound}}

	{{refimprove\|date=August 2014}}		{{refimprove\|date=August 2014}}

Latest revision as of 20:29, 29 January 2023

Chemical compound

This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.
Find sources: "Tetroxoprim" – news · newspapers · books · scholar · JSTOR (August 2014) (Learn how and when to remove this message)

Pharmaceutical compound

Tetroxoprim
Clinical data

ATC code	J01EE06 (WHO) (with sulfadiazine)
Identifiers
IUPAC name 5-pyrimidine-2,4-diamine
CAS Number	53808-87-0
PubChem CID	65450
ChemSpider	58910
UNII	5R6712AY0K
KEGG	D06097
ChEMBL	ChEMBL32039
CompTox Dashboard (EPA)	DTXSID80202085
ECHA InfoCard	100.053.427
Chemical and physical data
Formula	C₁₆H₂₂N₄O₄
Molar mass	334.376 g·mol
3D model (JSmol)	Interactive image
SMILES COCCOC1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC
InChI InChI=1S/C16H22N4O4/c1-21-4-5-24-14-12(22-2)7-10(8-13(14)23-3)6-11-9-19-16(18)20-15(11)17/h7-9H,4-6H2,1-3H3,(H4,17,18,19,20) Key:WSWJIZXMAUYHOE-UHFFFAOYSA-N
(what is this?) (verify)

Tetroxoprim (INN) is a derivative of trimethoprim. It was first described in 1979.

Its chemical formula is C=16 | H=22 | N=4 | O=4.

Aschhoff HS, Vergin H (November 1979). "Tetroxoprim—a new inhibitor of bacterial dihydrofolate reductase". J Antimicrob Chemother. 5 (B): 19–25. doi:10.1093/jac/5.supplement_b.19. PMID 43863.
^ "Tetroxoprim". pubchem.ncbi.nlm.nih.gov.
^ "Tetroxoprim - an overview | ScienceDirect Topics". www.sciencedirect.com.

Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)

Short-acting	Sulfaisodimidine Sulfamethizole Sulfadimidine (Sulfamethazine, Sulfadimerazine, Sulfadimezine) Sulfapyridine (Sulfasalazine) Sulfafurazole (Acetyl sulfisoxazole) Sulfanilamide Prontosil Sulfathiazole (Phthalylsulfathiazole, Succinylsulfathiazole) Sulfathiourea
Intermediate-acting	Sulfamethoxazole Sulfadiazine Sulfamoxole
Long-acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone
Other/ungrouped	Mafenide Sulfacetamide Sulfaclozine Sulfadicramide Sulfaguanidine Sulfametrole Sulfanitran

Combinations

Other DHPS inhibitors

Quinolones
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)

2nd generation	Ciprofloxacin Ofloxacin Enoxacin Fleroxacin Lomefloxacin Nadifloxacin/Levonadifloxacin/Alalevonadifloxacin Norfloxacin Pefloxacin Rufloxacin
3rd generation	Levofloxacin Balofloxacin Grepafloxacin Pazufloxacin Sparfloxacin Temafloxacin Tosufloxacin
4th generation	Besifloxacin Delafloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin Garenoxacin Prulifloxacin Sitafloxacin Trovafloxacin/Alatrofloxacin
Veterinary	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitroimidazole derivatives	Secnidazole

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin Rifabutin Rifapentine Rifaximin Rifalazil
Lipiarmycins	Fidaxomicin

This systemic antibiotic-related article is a stub. You can help Misplaced Pages by expanding it.

Revision as of 19:43, 9 January 2023 editOzzie10aaaa (talk \| contribs)Autopatrolled, Extended confirmed users, New page reviewers214,346 edits no need← Previous edit		Latest revision as of 20:29, 29 January 2023 edit undoEntranced98 (talk \| contribs)Extended confirmed users, Pending changes reviewers, Rollbackers174,416 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper
Line 1:		Line 1:
			{{Short description\|Chemical compound}}

	{{refimprove\|date=August 2014}}		{{refimprove\|date=August 2014}}