| Revision as of 05:58, 15 June 2020 editBoghog (talk | contribs)Autopatrolled, Extended confirmed users, IP block exemptions, New page reviewers, Pending changes reviewers, Rollbackers, Template editors137,799 edits consistent citation formatting← Previous edit | Latest revision as of 13:13, 30 May 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers172,831 edits Adding local short description: "Monoclonal antibody", overriding Wikidata description "chemical compound"Tag: Shortdesc helper | ||
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Latest revision as of 13:13, 30 May 2023
Monoclonal antibody Pharmaceutical compound| Monoclonal antibody | |
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| Type | Whole antibody |
| Source | Mouse |
| Target | endotoxin |
| Clinical data | |
| Routes of administration | Intravenous infusion |
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Edobacomab, codenamed E5, is a mouse monoclonal antibody that was investigated as a possible treatment for sepsis caused by Gram-negative bacterial infections.
Further reading
- Greenman RL, Schein RM, Martin MA, Wenzel RP, MacIntyre NR, Emmanuel G, et al. (August 1991). "A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group". JAMA. 266 (8): 1097–102. doi:10.1001/jama.266.8.1097. PMID 1865542.
- Bone RC, Balk RA, Fein AM, Perl TM, Wenzel RP, Reines HD, et al. (June 1995). "A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group". Critical Care Medicine. 23 (6): 994–1006. doi:10.1097/00003246-199506000-00003. PMID 7774238.
- Angus DC, Birmingham MC, Balk RA, Scannon PJ, Collins D, Kruse JA, et al. (April 2000). "E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators". JAMA. 283 (13): 1723–30. doi:10.1001/jama.283.13.1723. PMID 10755499.
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 | This antiinfective drug article is a stub. You can help Misplaced Pages by expanding it. |
 | This monoclonal antibody–related article is a stub. You can help Misplaced Pages by expanding it. |