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Feprazone: Difference between revisions

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'''Feprazone''' (or '''prenazone''') is a drug used for joint and muscular ].<ref>{{cite journal | vauthors = Koyama T, Izawa Y, Wada H, Makita T, Hashimoto Y, Enomoto M | title = Toxicological aspects of feprazone, a new nonsteroidal anti-inflammatory drug | journal = Toxicology and Applied Pharmacology | volume = 64 | issue = 2 | pages = 255–70 | date = June 1982 | pmid = 7123554 | doi = 10.1016/0041-008X(82)90222-8 }}</ref> '''Feprazone''' (or '''prenazone''') is a drug used for joint and muscular ].<ref>{{cite journal | vauthors = Koyama T, Izawa Y, Wada H, Makita T, Hashimoto Y, Enomoto M | title = Toxicological aspects of feprazone, a new nonsteroidal anti-inflammatory drug | journal = Toxicology and Applied Pharmacology | volume = 64 | issue = 2 | pages = 255–70 | date = June 1982 | pmid = 7123554 | doi = 10.1016/0041-008X(82)90222-8 | bibcode = 1982ToxAP..64..255K }}</ref>


It is an analog of ] but instead of a ''n''-butyl group it is ]. It is an analog of ] but instead of a ''n''-butyl group it is ].

Revision as of 15:53, 9 December 2024

NSAID analgesic drug Pharmaceutical compound
Feprazone
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 4-(3-methylbut-2-enyl)-1,2-di(phenyl)pyrazolidine-3,5-dione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.045.735 Edit this at Wikidata
Chemical and physical data
FormulaC20H20N2O2
Molar mass320.392 g·mol
3D model (JSmol)
SMILES
  • O=C2N(c1ccccc1)N(C(=O)C2C\C=C(/C)C)c3ccccc3
InChI
  • InChI=1S/C20H20N2O2/c1-15(2)13-14-18-19(23)21(16-9-5-3-6-10-16)22(20(18)24)17-11-7-4-8-12-17/h3-13,18H,14H2,1-2H3
  • Key:RBBWCVQDXDFISW-UHFFFAOYSA-N
  (verify)

Feprazone (or prenazone) is a drug used for joint and muscular pain.

It is an analog of phenylbutazone but instead of a n-butyl group it is prenylated.

References

  1. Koyama T, Izawa Y, Wada H, Makita T, Hashimoto Y, Enomoto M (June 1982). "Toxicological aspects of feprazone, a new nonsteroidal anti-inflammatory drug". Toxicology and Applied Pharmacology. 64 (2): 255–70. Bibcode:1982ToxAP..64..255K. doi:10.1016/0041-008X(82)90222-8. PMID 7123554.
Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones /
pyrazolidines
salicylates
acetic acid derivatives
and related substances
oxicams
propionic acid
derivatives (profens)
n-arylanthranilic
acids (fenamates)
COX-2 inhibitors
(coxibs)
other
NSAID
combinations
Key: underline indicates initially developed first-in-class compound of specific group; WHO-Essential Medicines; withdrawn drugs; veterinary use.
Topical products for joint and muscular pain (M02)
Anti-inflammatory
preparations,
non-steroids
Pyrazolidines
Acetic acid
derivatives
Other
Capsaicin derivatives
Other
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