| Revision as of 18:11, 18 November 2007 editLeevanjackson (talk | contribs)Extended confirmed users, Pending changes reviewers6,619 edits have cleared jargon,gaba not in anymore,nor is proteasome,nor nanotube!← Previous edit | Revision as of 22:48, 19 November 2007 edit undoLeevanjackson (talk | contribs)Extended confirmed users, Pending changes reviewers6,619 edits doneNext edit → | ||
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| from discussion | from discussion | ||
| *images/graphs of age of onset, distribution of CAG repeats,maybe the huntingtin molecule - (possibly as main image) | *images/graphs of age of onset, distribution of CAG repeats,maybe the huntingtin molecule - (possibly as main image) | ||
| *it would be much appreciated if something could be added regarding Pre-Implantation Genetic Diagnosis as an option for having children without passing the gene forward. Although there are still ethical considerations, they may be more bearable than the choice to abort or not. | |||
Revision as of 22:48, 19 November 2007
from peer review
- The "Genetics" section mentions that repeat number becomes unstable after 35 repeats and causes disease after 40. It should either be briefly explained why the DNA replication machinery has difficulty with repetitive sequences, or at least wikilink to DNA replication so readers can learn about it there.
- The "Epidemiology" section could use some expansion if the data is available. Is it more prevalent in certain populations or ethnic groups? The prevalence statement also needs a citation, and there are weasel words in the ethics section.
from discussion
- images/graphs of age of onset, distribution of CAG repeats,maybe the huntingtin molecule - (possibly as main image)