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Revision as of 22:48, 19 November 2007 editLeevanjackson (talk | contribs)Extended confirmed users, Pending changes reviewers6,619 edits done← Previous edit Revision as of 03:04, 1 April 2008 edit undoLeevanjackson (talk | contribs)Extended confirmed users, Pending changes reviewers6,619 edits organisd and added couple of ideasNext edit →
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from peer review from peer review
* The "Genetics" section mentions that repeat number becomes unstable after 35 repeats and causes disease after 40. It should either be briefly explained why the DNA replication machinery has difficulty with repetitive sequences, or at least wikilink to DNA replication so readers can learn about it there. * The "Genetics" section mentions that repeat number becomes unstable after 35 repeats and causes disease after 40. It should either be briefly explained why the DNA replication machinery has difficulty with repetitive sequences, or at least wikilink to DNA replication so readers can learn about it there.
* The "Epidemiology" section could use some expansion if the data is available. Is it more prevalent in certain populations or ethnic groups? The prevalence statement also needs a citation, and there are weasel words in the ethics section. * The "Epidemiology" section could use some expansion if the data is available. Is it more prevalent in certain populations or ethnic groups? The prevalence statement also needs a citation,
*weasel words in the ethics section.
from discussion from elsewhere including discussion
*images
⚫ *images/graphs of age of onset, distribution of CAG repeats,maybe the huntingtin molecule - (possibly as main image)
**graphs of age of onset vs distribution of CAG repeats
⚫ **maybe the huntingtin molecule - (possibly as main image)
**image of areas of brain affected
**Epidemiology global map of prevalence
*history section as prose?

Revision as of 03:04, 1 April 2008

from peer review

  • The "Genetics" section mentions that repeat number becomes unstable after 35 repeats and causes disease after 40. It should either be briefly explained why the DNA replication machinery has difficulty with repetitive sequences, or at least wikilink to DNA replication so readers can learn about it there.
  • The "Epidemiology" section could use some expansion if the data is available. Is it more prevalent in certain populations or ethnic groups? The prevalence statement also needs a citation,
  • weasel words in the ethics section.

from elsewhere including discussion

  • images
    • graphs of age of onset vs distribution of CAG repeats
    • maybe the huntingtin molecule - (possibly as main image)
    • image of areas of brain affected
    • Epidemiology global map of prevalence
  • history section as prose?