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{{Drugbox| {{Drugbox|
|IUPAC_name = ''N''--''N'''-(2-{thio}ethyl)guanidine |IUPAC_name = ''N''--''N'''-(2-{thio}ethyl)guanidine
| image=Impromidine.png | image=Impromidine.svg
| CAS_number=55273-05-7 | CAS_number=55273-05-7
| ATC_prefix=none | ATC_prefix=none

Revision as of 07:52, 13 August 2010

{{Drugbox| |IUPAC_name = N--N'-(2-{thio}ethyl)guanidine | image=Impromidine.svg | CAS_number=55273-05-7 | ATC_prefix=none | ATC_suffix= | PubChem= 41376 | IUPHAR_ligand = 1226 | DrugBank= | smiles = Cc2ncnc2CSCCNC(N)=NCCCc1cncn1 | C=14 | H=23 | N=7 | S=1 | molecular_weight = 321.44 g/mol | bioavailability= | metabolism = | elimination_half-life= | excretion = | pregnancy_category = | legal_status = | routes_of_administration= }} Impromidine (INN) is a highly potent and specific histamine H2 receptor agonist.

It has been used diagnostically as a gastric secretion indicator.

See Histamine agonists.

References

  1. Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature. 276 (5686): 403–5. doi:10.1038/276403a0. PMID 714166.{{cite journal}}: CS1 maint: multiple names: authors list (link)
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Histamine receptor modulators
H1
Agonists
Antagonists
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
See also
Receptor/signaling modulators
Monoamine metabolism modulators
Monoamine reuptake inhibitors
Categories: