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Amlodipine/atorvastatin: Difference between revisions

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Revision as of 10:42, 12 November 2010 editBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: StdInChI StdInChIKey.← Previous edit Revision as of 13:31, 18 April 2011 edit undo58.111.66.244 (talk)No edit summaryNext edit →
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| routes_of_administration = Oral | routes_of_administration = Oral
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The drug combination '''atorvastatin/amlodipine''' (trade names '''Caduet''' in the ] and '''Envacar''' elsewhere) is a medication approved by the ] (FDA) for the treatment of ] and ]. It is a ] drug containing the ] ] and the ] ]. It is being marketed by the ] ].<ref>{{cite web|url=http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm202933.htm|format=PDF|title=CADUET (amlodipine besylate/atorvastatin calcium) Tablets|month=February | year=2010|work=NDA 21-540/S-009|publisher=]|accessdate=2010-09-25}}</ref> The drug combination '''atorvastatin/amlodipine''' (trade names '''Caduet''' in the ] and ], and '''Envacar''' elsewhere) is a medication approved by the ] (FDA) for the treatment of ] and ]. It is a ] drug containing the ] ] and the ] ]. It is being marketed by the ] ].<ref>{{cite web|url=http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm202933.htm|format=PDF|title=CADUET (amlodipine besylate/atorvastatin calcium) Tablets|month=February | year=2010|work=NDA 21-540/S-009|publisher=]|accessdate=2010-09-25}}</ref>


== References == == References ==

Revision as of 13:31, 18 April 2011

Pharmaceutical compound
Amlodipine/atorvastatin
Combination of
AmlodipineCalcium channel blocker
AtorvastatinStatin
Clinical data
Routes of
administration		Oral
ATC code
Legal status
Legal status
Identifiers
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
3D model (JSmol)
SMILES
  • Clc1ccccc1C2C(\C(=O)OC)=C(/N\C(=C2\C(=O)OCC)COCCN)C.O=C(O)C(O)C(O)CCn2c(c(c(c2c1ccc(F)cc1)c3ccccc3)C(=O)Nc4ccccc4)C(C)C
InChI
  • InChI=1S/C33H35FN2O5.C20H25ClN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);5-8,17,23H,4,9-11,22H2,1-3H3/t26-,27-;/m1./s1
  • Key:PEAJXAZCGDWDGS-CNZCJKERSA-N

The drug combination atorvastatin/amlodipine (trade names Caduet in the US and Australia, and Envacar elsewhere) is a medication approved by the Food and Drug Administration (FDA) for the treatment of high cholesterol and high blood pressure. It is a fixed dose combination drug containing the calcium channel blocker amlodipine and the statin atorvastatin. It is being marketed by the pharmaceutical company Pfizer.

References

  1. "CADUET (amlodipine besylate/atorvastatin calcium) Tablets" (PDF). NDA 21-540/S-009. United States Food and Drug Administration. 2010. Retrieved 2010-09-25. {{cite web}}: Unknown parameter |month= ignored (help)

External links


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