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'''Butein''' is a ]. It can be found in '']'' (or formerly ''Rhus verniciflua''). It has ], ] and ]s inhibitory effects<ref name="pmid18670102">{{cite journal |author=Lee EH, Song DG, Lee JY, Pan CH, Um BH, Jung SH |title=Inhibitory effect of the compounds isolated from Rhus verniciflua on aldose reductase and advanced glycation endproducts |journal=Biol. Pharm. Bull. |volume=31 |issue=8 |pages=1626–30 |year=2008 |month=August |pmid=18670102 |doi= 10.1248/bpb.31.1626|url=http://joi.jlc.jst.go.jp/JST.JSTAGE/bpb/31.1626?from=PubMed}}</ref>. It is also a ], a chemical compound having an effect on sirtuins, a group of enzymes that use NAD<sup>+</sup> to remove acetyl groups from proteins. '''Butein''' is a ]. It can be found in '']'' (or formerly ''Rhus verniciflua''). It has ], ] and ]s inhibitory effects<ref name="pmid18670102">{{cite journal |author=Lee EH, Song DG, Lee JY, Pan CH, Um BH, Jung SH |title=Inhibitory effect of the compounds isolated from Rhus verniciflua on aldose reductase and advanced glycation endproducts |journal=Biol. Pharm. Bull. |volume=31 |issue=8 |pages=1626–30 |year=2008 |month=August |pmid=18670102 |doi= 10.1248/bpb.31.1626|url=http://joi.jlc.jst.go.jp/JST.JSTAGE/bpb/31.1626?from=PubMed}}</ref>. It is also a ], a chemical compound having an effect on sirtuins, a group of enzymes that use NAD<sup>+</sup> to remove acetyl groups from proteins.


==References== ==References==
{{reflist}} {{reflist}}


{{chalcone}} {{chalconoid}}


] ]


{{Natural-phenol-stub}} {{Natural-phenol-stub}}
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Revision as of 12:08, 30 April 2011

Butein
Chemical structure of butein
Chemical structure of butein
Names
IUPAC name (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
Other names 2',3,4,4'-Tetrahydroxychalcone
2',4',3,4-Tetrahydroxychalcone
3,4,2',4'-Tetrahydroxychalcone
2′,4′,3,4-Tetrahydroxychalcone
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ECHA InfoCard 100.006.963 Edit this at Wikidata
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O
Properties
Chemical formula C15H12O5
Molar mass 272.25 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Butein is a chalconoid. It can be found in Toxicodendron vernicifluum (or formerly Rhus verniciflua). It has antioxidative, aldose reductase and advanced glycation endproducts inhibitory effects. It is also a sirtuin-activating compound, a chemical compound having an effect on sirtuins, a group of enzymes that use NAD to remove acetyl groups from proteins.

References

  1. Lee EH, Song DG, Lee JY, Pan CH, Um BH, Jung SH (2008). "Inhibitory effect of the compounds isolated from Rhus verniciflua on aldose reductase and advanced glycation endproducts". Biol. Pharm. Bull. 31 (8): 1626–30. doi:10.1248/bpb.31.1626. PMID 18670102. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
Chalconoids and their glycosides
Chalconoids
Chalconoid glycosides
Acylated chalconoids
O-methylated chalconoids
Flavokavains
Synthetic

Template:Natural-phenol-stub

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