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| ImageFile = Y-27632.svg | | ImageFile = Y-27632.svg | ||
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Revision as of 19:39, 3 August 2011
Names | |
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IUPAC name (1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide | |
Identifiers | |
CAS Number | |
3D model (JSmol) | |
ECHA InfoCard | 100.149.247 |
PubChem CID | |
CompTox Dashboard (EPA) | |
SMILES
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Properties | |
Chemical formula | C14H21N3O |
Molar mass | 247.342 g·mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references |
Y-27632 is a biochemical tool used in the study of the rho-associated protein kinase (ROCK) signaling pathways. Y-27632 selectively inhibits p160ROCK.
References
- Uehata, Masayoshi (1999). "Y-27632. Selective probe of ROCK/Rho-kinase". Jikken Igaku. 17 (7): 850–855.
- Uehata, M; Ishizaki, T; Satoh, H; Ono, T; Kawahara, T; Morishita, T; Tamakawa, H; Yamagami, K; Inui, J (1997). "Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension". Nature. 389 (6654): 990–4. doi:10.1038/40187. PMID 9353125.
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