| Revision as of 13:42, 18 April 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{drugbox}} (no changed fields - added verified revid - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (← Previous edit | Revision as of 20:09, 28 August 2011 edit undoBogBot (talk | contribs)Bots53,132 edits populated new fields in {{drugbox}} and reordered per bot approval. Report errors and suggestions to User_talk:BogBotNext edit → | ||
| Line 1: | Line 1: | ||
| {{Drugbox | {{Drugbox | ||
| | verifiedrevid = 396294114 | | verifiedrevid = 396294114 | ||
| ⚫ | | image = Amlodipine.png | ||
| ⚫ | | type |
||
| | |
| image2 = Lipitor.png | ||
| | image2 = Lipitor.png | |||
| <!--Combo data--> | |||
| ⚫ | | |
||
| ⚫ | | type = combo | ||
| ⚫ | | class1 |
||
| | component1 = Amlodipine | |||
| ⚫ | | component2 |
||
| ⚫ | | class1 = ] | ||
| ⚫ | | class2 |
||
| ⚫ | | component2 = Atorvastatin | ||
| ⚫ | | class2 = ] | ||
| <!--Clinical data--> | |||
| | tradename = | |||
| ⚫ | | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | ||
| ⚫ | | pregnancy_US = X | ||
| ⚫ | | pregnancy_category = | ||
| ⚫ | | legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | ||
| ⚫ | | legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> | ||
| ⚫ | | legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> | ||
| ⚫ | | legal_US = Rx-only | ||
| ⚫ | | legal_status = | ||
| ⚫ | | routes_of_administration = Oral | ||
| <!--Identifiers--> | |||
| ⚫ | | CAS_number = | ||
| ⚫ | | ATC_prefix = C10 | ||
| ⚫ | | ATC_suffix = BX03 | ||
| ⚫ | | PubChem = 9811759 | ||
| ⚫ | | DrugBank = | ||
| | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ||
| | ChemSpiderID = 7987512 | | ChemSpiderID = 7987512 | ||
| ⚫ | | InChI = 1/C33H35FN2O5.C20H25ClN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);5-8,17,23H,4,9-11,22H2,1-3H3/t26-,27-;/m1./s1 | ||
| <!--Chemical data--> | |||
| | smiles = Clc1ccccc1C2C(\C(=O)OC)=C(/N\C(=C2\C(=O)OCC)COCCN)C.O=C(O)C(O)C(O)CCn2c(c(c(c2c1ccc(F)cc1)c3ccccc3)C(=O)Nc4ccccc4)C(C)C | | smiles = Clc1ccccc1C2C(\C(=O)OC)=C(/N\C(=C2\C(=O)OCC)COCCN)C.O=C(O)C(O)C(O)CCn2c(c(c(c2c1ccc(F)cc1)c3ccccc3)C(=O)Nc4ccccc4)C(C)C | ||
| ⚫ | | InChI = 1/C33H35FN2O5.C20H25ClN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);5-8,17,23H,4,9-11,22H2,1-3H3/t26-,27-;/m1./s1 | ||
| | InChIKey = PEAJXAZCGDWDGS-CNZCJKERBU | | InChIKey = PEAJXAZCGDWDGS-CNZCJKERBU | ||
| | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | ||
| Line 17: | Line 40: | ||
| | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | ||
| | StdInChIKey = PEAJXAZCGDWDGS-CNZCJKERSA-N | | StdInChIKey = PEAJXAZCGDWDGS-CNZCJKERSA-N | ||
| ⚫ | | CAS_number |
||
| ⚫ | | ATC_prefix |
||
| ⚫ | | ATC_suffix |
||
| ⚫ | | PubChem = 9811759 | ||
| ⚫ | | DrugBank |
||
| ⚫ | | pregnancy_AU |
||
| ⚫ | | pregnancy_US |
||
| ⚫ | | pregnancy_category= | ||
| ⚫ | | legal_AU |
||
| ⚫ | | legal_CA |
||
| ⚫ | | legal_UK |
||
| ⚫ | | legal_US |
||
| ⚫ | | legal_status |
||
| ⚫ | | routes_of_administration = Oral | ||
| }} | }} | ||
| The drug combination '''atorvastatin/amlodipine''' (trade names '''Caduet''' in the ] and ], and '''Envacar''' elsewhere) is a medication approved by the ] (FDA) for the treatment of ] and ]. It is a ] drug containing the ] ] and the ] ]. It is being marketed by the ] ].<ref>{{cite web|url=http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm202933.htm|format=PDF|title=CADUET (amlodipine besylate/atorvastatin calcium) Tablets|month=February | year=2010|work=NDA 21-540/S-009|publisher=]|accessdate=2010-09-25}}</ref> | The drug combination '''atorvastatin/amlodipine''' (trade names '''Caduet''' in the ] and ], and '''Envacar''' elsewhere) is a medication approved by the ] (FDA) for the treatment of ] and ]. It is a ] drug containing the ] ] and the ] ]. It is being marketed by the ] ].<ref>{{cite web|url=http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm202933.htm|format=PDF|title=CADUET (amlodipine besylate/atorvastatin calcium) Tablets|month=February | year=2010|work=NDA 21-540/S-009|publisher=]|accessdate=2010-09-25}}</ref> | ||
Revision as of 20:09, 28 August 2011
Pharmaceutical compound | |
 | |
| Combination of | |
|---|---|
| Amlodipine | Calcium channel blocker |
| Atorvastatin | Statin |
| Clinical data | |
| Routes of administration | Oral |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| PubChem CID | |
| ChemSpider | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| 3D model (JSmol) | |
SMILES
| |
InChI
| |
| (verify) | |
The drug combination atorvastatin/amlodipine (trade names Caduet in the US and Australia, and Envacar elsewhere) is a medication approved by the Food and Drug Administration (FDA) for the treatment of high cholesterol and high blood pressure. It is a fixed dose combination drug containing the calcium channel blocker amlodipine and the statin atorvastatin. It is being marketed by the pharmaceutical company Pfizer.
References
- "CADUET (amlodipine besylate/atorvastatin calcium) Tablets" (PDF). NDA 21-540/S-009. United States Food and Drug Administration. 2010. Retrieved 2010-09-25.
{{cite web}}: Unknown parameter|month=ignored (help)
External links
- Manufacturer's site (caduet.com)
 | This drug article relating to the cardiovascular system is a stub. You can help Misplaced Pages by expanding it. |