| Revision as of 08:04, 1 November 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{drugbox}} (changes to verified fields - updated 'ChemSpiderID_Ref', 'ChEBI_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref') per Chem/Drugbox validation (report errors or [[user talk:C...← Previous edit | Revision as of 09:32, 1 November 2011 edit undoBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'ChEMBL').Next edit → | ||
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Revision as of 09:32, 1 November 2011
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Idursulfase (brand name Elaprase) is a drug used to treat Hunter syndrome (also called Mucopolysaccharoidosis II). It is a purified form of the lysosomal enzyme iduronate-2-sulfatase and is produced by recombinant DNA technology in a human cell line.
It is one of the most expensive drugs ever produced, costing $375,000 per year.
It is manufactured by Shire Pharmaceuticals Group.
References
- "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 Oct 2023.
- Garcia AR, DaCosta JM, Pan J, Muenzer J, Lamsa JC (2007). "Preclinical dose ranging studies for enzyme replacement therapy with idursulfase in a knock-out mouse model of MPS II". Mol. Genet. Metab. 91 (2): 183–90. doi:10.1016/j.ymgme.2007.03.003. PMID 17459751.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - "Drug approved to treat rare but potentially deadly disease". Retrieved 2011-04-29.
- Health Care: The World's Most Expensive Drugs, Matthew Herper, Forbes, Feb. 22, 2010
External links
- idursulfase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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