Revision as of 21:05, 1 November 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{drugbox}} (no changed fields - added verified revid - updated 'ChemSpiderID_Ref', 'UNII_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'CAS_number_Ref') per Chem/Drugbox validation (repo...← Previous edit | Revision as of 21:17, 1 November 2011 edit undoBearcat (talk | contribs)Autopatrolled, Administrators1,570,388 edits →References: categorization/tagging, removed: {{Uncategorized|date=November 2011}} using AWBNext edit → | ||
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Revision as of 21:17, 1 November 2011
Pharmaceutical compoundMonoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | E. coli Shiga-like toxin II B subunit |
Clinical data | |
ATC code |
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Identifiers | |
CAS Number | |
Chemical and physical data | |
Formula | C6414H9934N1718O2010S40 |
Molar mass | 144.6 kDa g·mol |
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Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.
References
- International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
- López, EL; Contrini, MM; Glatstein, E; González Ayala, S; Santoro, R; Allende, D; Ezcurra, G; Teplitz, E; Koyama, T (2009). "Safety and Pharmacokinetics of Urtoxazumab, a Humanized Monoclonal Antibody Against Shiga-Like Toxin 2 in Healthy Adults and Pediatric STEC- Infected Patients". Antimicrobial agents and chemotherapy. 54 (1): 239–243. doi:10.1128/AAC.00343-09. PMC 2798559. PMID 19822704.
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