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Revision as of 10:54, 6 December 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{drugbox}} taken from revid 464344515 of page Lefetamine for the Chem/Drugbox validation project (updated: 'CAS_number').← Previous edit Revision as of 10:56, 6 December 2011 edit undoBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{drugbox}} taken from revid 464290800 of page Lidocaine for the Chem/Drugbox validation project (updated: '').Next edit →
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} {{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}}
{{Drugbox {{Drugbox| Verifiedfields = changed
| verifiedrevid = 451642269 | verifiedrevid = 417820511
| IUPAC_name = (1''R'')-''N'',''N''-dimethyl-1,2-diphenylethanamine | IUPAC_name = 2-(diethylamino)-<br />''N''-(2,6-dimethylphenyl)acetamide
| image = Lefetamine.svg | image = Lidocaine.svg
| width = 200px
| image2 = Lefetamine3d.png
| image2 = Lidocaine-from-xtal-3D-balls.png
| width2 = 160 | width2 = 200px


<!--Clinical data--> <!--Clinical data-->
| tradename = | tradename = Xylocaine
| Drugs.com = {{drugs.com|CONS|lidocaine}}
| pregnancy_category =
| pregnancy_AU = A
| legal_status = ] (])
| pregnancy_US = B
| routes_of_administration = ]
| legal_AU = S4
| legal_US = Rx Only (U.S.) (excluding 1%)
| routes_of_administration = ], ], ]


<!--Pharmacokinetic data--> <!--Pharmacokinetic data-->
| bioavailability = | bioavailability = 35% (oral) <br /> 3% (topical)
| metabolism = | metabolism = ], 90% ]-mediated
| elimination_half-life = | elimination_half-life = 1.5–2 hours
| excretion = | excretion = ]


<!--Identifiers--> <!--Identifiers-->
| CASNo_Ref = {{cascite|correct|CAS}}
| CAS_number_Ref = {{cascite|correct|??}} | CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = <!-- blanked - oldvalue: 7262-75-1 --> | CAS_number = 137-58-6
| CAS_supplemental = <br/>{{CAS|73-78-9}} (hydrochloride)
| ATC_prefix = none
| ATC_suffix = | ATC_prefix = N01
| PubChem = 443970 | ATC_suffix = BB02
| ATC_supplemental = {{ATC|C01|BB01}} {{ATC|D04|AB01}} {{ATC|S02|DA01}} {{ATC|C05|AD01}}
| PubChem = 3676
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB00281
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 392017 | ChemSpiderID = 3548
| UNII_Ref = {{fdacite|correct|FDA}} | UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 4J9726V5Y9 | UNII = 98PI200987
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00358
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 6456
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 79


<!--Chemical data--> <!--Chemical data-->
| C=16 | H=19 | N=1 | C=14 | H=22 | N=2 | O=1
| molecular_weight = 225.329 g/mol | molecular_weight = 234.34 g/mol
| smiles = N(C)((c1ccccc1)Cc2ccccc2)C | smiles = O=C(Nc1c(cccc1C)C)CN(CC)CC
| InChI = 1/C16H19N/c1-17(2)16(15-11-7-4-8-12-15)13-14-9-5-3-6-10-14/h3-12,16H,13H2,1-2H3/t16-/m1/s1 | InChI = 1/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
| InChIKey = YEJZJVJJPVZXGX-MRXNPFEDBZ
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C16H19N/c1-17(2)16(15-11-7-4-8-12-15)13-14-9-5-3-6-10-14/h3-12,16H,13H2,1-2H3/t16-/m1/s1 | StdInChI = 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = YEJZJVJJPVZXGX-MRXNPFEDSA-N | StdInChIKey = NNJVILVZKWQKPM-UHFFFAOYSA-N
| synonyms = ''N''-(2,6-dimethylphenyl)-''N''<sup>2</sup>,''N''<sup>2</sup>-diethylglycinamide
| melting_point = 68
}} }}

Revision as of 10:56, 6 December 2011

This page contains a copy of the infobox ({{drugbox}}) taken from revid 464290800 of page Lidocaine with values updated to verified values.
WikiProject Chemicals/Chembox validation/VerifiedDataSandbox
Clinical data
Trade namesXylocaine
Other namesN-(2,6-dimethylphenyl)-N,N-diethylglycinamide
AHFS/Drugs.comMicromedex Detailed Consumer Information
Pregnancy
category
  • AU: A
Routes of
administration
IV, subcutaneous, topical
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • US: Rx Only (U.S.) (excluding 1%)
Pharmacokinetic data
Bioavailability35% (oral)
3% (topical)
MetabolismHepatic, 90% CYP1A2-mediated
Elimination half-life1.5–2 hours
Excretionrenal
Identifiers
IUPAC name
  • 2-(diethylamino)-
    N-(2,6-dimethylphenyl)acetamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC14H22N2O
Molar mass234.34 g/mol g·mol
3D model (JSmol)
Melting point68 °C (154 °F)
SMILES
  • O=C(Nc1c(cccc1C)C)CN(CC)CC
InChI
  • InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
  • Key:NNJVILVZKWQKPM-UHFFFAOYSA-N
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