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| logo = ] | | logo = ] | | ||
| foundation = 1992 |Joseph A. Mollica, Chairman | foundation = 1992 |Joseph A. Mollica, Chairman | ||
| Kevin Gorman, CEO/President | |||
| Tim Coughlin, CFO/Exec. VP| | |||
| location = ], ], ] | | location = ], ], ] | | ||
| key_people = ], Chairman <br />], CEO/President | | key_people = ], Chairman <br />], CEO/President | | ||
| num_employees = |
num_employees = 95 (2015) | | ||
| industry = ]| | industry = ]| | ||
| homepage = | | homepage = | | ||
| }} | }} | ||
| '''Neurocrine Biosciences''' | |||
| '''Neurocrine Biosciences''' is a biopharmaceutical company founded in 1992 and located in ], ]. The company tooks its name from the original focus on therapies for ] and ] ]s and disorders. | |||
| Neurocrine Biosciences, Inc. of San Diego discovers and develops innovative and life-changing pharmaceuticals, in diseases with high unmet medical needs, through its novel R&D platform, focused on neurological and endocrine based diseases and disorders. | |||
| The Company’s two lead late-stage clinical programs are elagolix, a gonadotropin-releasing hormone antagonist for women’s health that is partnered with AbbVie Inc., and a wholly owned vesicular monoamine transporter 2 inhibitor for the treatment of movement disorders. Neurocrine intends to maintain certain commercial rights to its VMAT2 inhibitor for evolution into a fully-integrated pharmaceutical company. | |||
| The company endured a significant setback on May 16, 2006 when the ] (FDA) denied approval for the 15-milligram dose of ], a medication to treat insomnia. Neurocrine had developed the drug and was seeking to market it with partner, ]. Announcement of the setback led to a 62% drop in stock price. Subsequent disclosures related to attempts to overcome this major setback caused a further drop in the stock by 30% in November 2006. | |||
| RESEARCH AND DEVELOPMENT PROGRAMS | |||
| Lacking approval for Indiplon, the company laid off a 200-member sales force in July, 2006 and 100 employees across all areas of the company on August 7, 2006. It announced a further cut of half the remaining workforce in December 2007, and a fourth quarter loss of $128 million, including a $94 million write-off.<ref>{{cite news |title=Write-Off Swells Neurocrine's 4Q Loss |url=http://money.cnn.com/news/newsfeeds/articles/apwire/449c555bdf80888e2d2b2b9228ea2c18.htm |date=2008-02-05 |publisher=]}}</ref> | |||
| But recently the company has recovered the long term hope for recovery. All started on the 25th of May, 2010 when the shares jumped nearly 25% after the company announced its drug to treat endometriosis had achieved its main and secondary goals in a study. | |||
| The drug, called elagolix, reportedly showed statistically significant reductions in dysmenorrhea, or pelvic pain during menstruation as well as painful intercourse. And the shares of the company were up 69 cents to $3.40 on May the 25th trading, hitting a 52-week high of $4.23 early in the trading session.<ref>{{cite news |title=Neurocrine Biosciences Shares Soar on Drug Trial |url=http://www.foxbusiness.com/story/markets/industries/health-care/neurocrine-biosciences-shares-soar-drug-trial/ |date=2010-05-25 |publisher=]}}</ref> | |||
| But since that the stock has climbed from $4.23 to $6.16 at 25 June 2010. And the expectatives for NBIX has raised about the elagolix trial success and of the sign for development deal with Boehringer.<ref>{{cite news |title=Neurocrine signs development deal with Boehringer |url=http://biz.yahoo.com/ap/100617/us_neurocrine_biosciences_contract.html?.v=1 |date=2010-06-17 |publisher=]}}</ref> and Abbott Laboratories.<ref>{{cite news |title=Abbott And Neurocrine Ink Endometriosis Drug Deal |url=http://us.rd.yahoo.com/finance/external/forbes/SIG=139b4dhp7/*http%3A//www.forbes.com/2010/06/16/abbott-neurocrine-partner-on-endometriosis-drug-marketnewsvideo.html?partner=yahootix |date=2010-06-16 |publisher=]}}</ref> | |||
| Neurocrine’s Research Group continues to advance novel small molecule compounds into clinical development. Neurocrine scientists are focusing on developing small molecule antagonists against G-protein coupled receptors. Our scientists possess the skills and experience necessary to bring compounds from basic research concepts to drug candidate stage. Neurocrine utilizes advanced technologies to enhance its drug discovery capabilities and to accelerate the drug development process. Working together, Neurocrine’s chemists, pharmacologists and biologists strive to create new solutions to unmet medical problems. | |||
| ==References== | ==References== | ||
| {{Reflist}} | {{Reflist}} | ||
Revision as of 21:06, 4 May 2015
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| Neurocrine logo | |
| Company type | Public Nasdaq: NBIX |
|---|---|
| Industry | Biotechnology |
| Founded | 1992 |
| Headquarters | San Diego, California, U.S. |
| Key people | Bill Rasetter, Chairman Kevin Gorman, CEO/President |
| Number of employees | 95 (2015) |
| Website | www.neurocrine.com |
Neurocrine Biosciences Neurocrine Biosciences, Inc. of San Diego discovers and develops innovative and life-changing pharmaceuticals, in diseases with high unmet medical needs, through its novel R&D platform, focused on neurological and endocrine based diseases and disorders.
The Company’s two lead late-stage clinical programs are elagolix, a gonadotropin-releasing hormone antagonist for women’s health that is partnered with AbbVie Inc., and a wholly owned vesicular monoamine transporter 2 inhibitor for the treatment of movement disorders. Neurocrine intends to maintain certain commercial rights to its VMAT2 inhibitor for evolution into a fully-integrated pharmaceutical company.
RESEARCH AND DEVELOPMENT PROGRAMS
Neurocrine’s Research Group continues to advance novel small molecule compounds into clinical development. Neurocrine scientists are focusing on developing small molecule antagonists against G-protein coupled receptors. Our scientists possess the skills and experience necessary to bring compounds from basic research concepts to drug candidate stage. Neurocrine utilizes advanced technologies to enhance its drug discovery capabilities and to accelerate the drug development process. Working together, Neurocrine’s chemists, pharmacologists and biologists strive to create new solutions to unmet medical problems.
References
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