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Azosemide: Difference between revisions

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Revision as of 21:23, 23 January 2018 editKolbertBot (talk | contribs)Bots1,166,042 editsm Bot: HTTP→HTTPS (v481)← Previous edit Revision as of 15:33, 6 October 2018 edit undoSMILESmaster (talk | contribs)Extended confirmed users511 edits fixed SMILESNext edit →
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| C=12 | H=11 | Cl=1 | N=6 | O=2 | S=2 | C=12 | H=11 | Cl=1 | N=6 | O=2 | S=2
| molecular_weight = 370.84 g/mol | molecular_weight = 370.84 g/mol
| smiles = O=S(=O)(N)c2c(Cl)cc(c(c1nnnn1)c2)NCc3sccc3 | smiles = O=S(=O)(N)c2c(Cl)cc(c(c1nnn1)c2)NCc3sccc3
}} }}


Revision as of 15:33, 6 October 2018

Pharmaceutical compound
Azosemide
Structural formula of azosemide
Space-filling model of the azosemide molecule
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
  • none
Identifiers
IUPAC name
  • 2-chloro-5-(2H-tetrazol-5-yl)-4-benzenesulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.044.121 Edit this at Wikidata
Chemical and physical data
FormulaC12H11ClN6O2S2
Molar mass370.84 g/mol g·mol
3D model (JSmol)
SMILES
  • O=S(=O)(N)c2c(Cl)cc(c(c1nnn1)c2)NCc3sccc3
InChI
  • InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19)
  • Key:HMEDEBAJARCKCT-UHFFFAOYSA-N
  (what is this?)  (verify)

Azosemide is a high-ceiling loop diuretic agent that was brought to market in 1981 by Boehringer Mannheim. As of 2015 it was available as a generic in some Asian countries.

References

  1. Marshall Sittig (1988). Pharmaceutical Manufacturing Encyclopedia (PDF). Vol. 1. Noyes Publications. p. 122. ISBN 9780815511441. Archived from the original (PDF) on 2007-10-23. {{cite book}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  2. Dieter Borman. Diuretics. Chapter 11 in Annual Reports in Medicinal Chemistry, Volume 15. Ed Hess, HJ.. Academic Press, 1980 ISBN 9780080583594
  3. Drugs.com Drugs.com international listings for azosemide Page accessed July 12, 2015
Diuretics (C03)
Sulfonamides
(and etacrynic acid)
CA inhibitors (at PT)
Loop (Na-K-Cl at AL)
Thiazides (Na-Cl at DCT,
Calcium-sparing)
Thiazide-likes (primarily DCT)
Potassium-sparing (at CD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT, DL)
Vasopressin receptor inhibitors
(DCT and CD)
Other
Combination products
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