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Citiolone: Difference between revisions

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'''Citiolone''' is a drug used in ] therapy.
⚫ '''Citiolone''' is a drug used in liver therapy. It is a derivative of the ] ].<ref>{{cite journal |vauthors=de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T |title=Recurrent fixed drug eruption caused by citiolone |journal=Journal of Investigational Allergology & Clinical Immunology |volume=7 |issue=3 |pages=193–4 |year=1997 |pmid=9252880 }}</ref> Citilone has also been studied with regards to hypothermia due to it being a hydroxyl free radical scavenger. The drug has been shown to protect hamster cells subjected to temperature conditions of 8-25&nbsp;°C.<ref>{{Cite journal|last=Kruuv|first=J.|last2=Glofcheski|first2=D.J.|title=Further Evidence for Two Modes of Hypothermia Damage|journal=Cryobiology|volume=30|issue=3|pages=313–321|doi=10.1006/cryo.1993.1030|pmid=8370318|year=1993}}</ref>

⚫ It is a derivative of the ] ].<ref>{{cite journal |vauthors=de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T |title=Recurrent fixed drug eruption caused by citiolone |journal=Journal of Investigational Allergology & Clinical Immunology |volume=7 |issue=3 |pages=193–4 |year=1997 |pmid=9252880 }}</ref> Citilone has also been studied with regards to ] due to it being a ] free radical scavenger. The drug has been shown to protect ] cells subjected to temperature conditions of 8-25&nbsp;°C.<ref>{{Cite journal|last=Kruuv|first=J.|last2=Glofcheski|first2=D.J.|title=Further Evidence for Two Modes of Hypothermia Damage|journal=Cryobiology|volume=30|issue=3|pages=313–321|doi=10.1006/cryo.1993.1030|pmid=8370318|year=1993}}</ref>


==References== ==References==

Revision as of 15:21, 7 October 2020

Pharmaceutical compound
Citiolone
Clinical data
ATC code
Identifiers
IUPAC name
  • (RS)-N-(2-Oxothiolan-3-yl)acetamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.013.449 Edit this at Wikidata
Chemical and physical data
FormulaC6H9NO2S
Molar mass159.20 g·mol
InChI
  • InChI=1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8)
  • Key:NRFJZTXWLKPZAV-UHFFFAOYSA-N
  (what is this?)  (verify)

Citiolone is a drug used in liver therapy.

It is a derivative of the amino acid cysteine. Citilone has also been studied with regards to hypothermia due to it being a hydroxyl free radical scavenger. The drug has been shown to protect hamster cells subjected to temperature conditions of 8-25 °C.

References

  1. de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T (1997). "Recurrent fixed drug eruption caused by citiolone". Journal of Investigational Allergology & Clinical Immunology. 7 (3): 193–4. PMID 9252880.
  2. Kruuv, J.; Glofcheski, D.J. (1993). "Further Evidence for Two Modes of Hypothermia Damage". Cryobiology. 30 (3): 313–321. doi:10.1006/cryo.1993.1030. PMID 8370318.
Bile and liver therapy (A05)
Bile therapy
Liver therapy


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