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Revision as of 00:14, 5 December 2020 edit5.170.117.113 (talk) "External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for false positive results." zenodo.org/record/4298004← Previous edit Revision as of 06:38, 5 December 2020 edit undoLowercase sigmabot III (talk | contribs)Bots, Template editors2,304,775 editsm Archiving 1 discussion(s) to Talk:COVID-19 testing/Archive 3) (botTag: RevertedNext edit →
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--] (]) 12:37, 25 September 2020 (UTC) --] (]) 12:37, 25 September 2020 (UTC)
:] '''Already done'''<!-- Template:EP --> ] ] 03:46, 19 October 2020 (UTC) :] '''Already done'''<!-- Template:EP --> ] ] 03:46, 19 October 2020 (UTC)

== Antigen testing ==

Is it worth adding this or should we wait until it actually rolls out ? IMO it should be added if it actually rolls out on a wide scale since while individual countries rolling out random tests can be too minor to mention, a widescale roll out which involves the WHO is significant enough to mention. ] (]) 09:40, 29 September 2020 (UTC)


== Sensitivity and Specificity == == Sensitivity and Specificity ==

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Section sizes
Section size for COVID-19 testing (60 sections)
Section name Byte
count
Section
total
(Top) 8,178 8,178
Methods 2,895 70,222
Detection of the virus 1,289 34,163
Reverse transcription polymerase chain reaction (RT-PCR) test 21,691 21,691
Other molecular tests 1,745 1,745
Antigen tests 9,438 9,438
Antibody tests 7,358 17,608
Antibody Test Types 30 2,561
Rapid diagnostic test (RDT) 814 814
Enzyme-linked immunosorbent assay (ELISA) 561 561
Neutralization assay 434 434
Chemiluminescent immunoassay 722 722
Neutralizing vis-à-vis binding antibodies 7,689 7,689
Other tests 19 15,556
Sniff tests 2,274 2,274
Imaging 8,173 8,173
Serology (CoLab score) tests 948 948
Breath tests 244 244
Animals 3,273 3,273
Functional assays 625 625
History 7,537 7,537
Testing protocols 25 24,869
Drive-through testing 1,978 1,978
Home collection 2,364 2,364
Pooled testing 8,060 8,060
Multi-tiered testing 702 702
Required volume 1,068 5,615
United States 4,547 4,547
Snapshot mass-testing 2,770 2,770
Surveillance and screening of populations 3,355 3,355
Available tests 259 13,773
Nucleic acid tests 3,174 3,174
Antigen tests 4,739 4,739
Serology (antibody) tests 5,601 5,601
Accuracy 2,025 15,500
Sensitivity and specificity 2,922 2,922
Causes of test error 902 902
PCR-based test 8,349 8,349
Isothermal nucleic amplification test 1,302 1,302
Confirmatory testing 2,100 2,100
National or regional responses 36 38,314
Iceland 629 629
India 77 77
Italy 691 691
Japan 15,022 15,022
Russia 1,252 1,252
Singapore 773 773
Slovakia 859 859
South Korea 10,463 10,463
Taiwan 2,185 2,185
United Arab Emirates 991 991
United States 70 5,336
New York State 2,899 2,899
USS Theodore Roosevelt 1,335 1,335
Nevada 1,032 1,032
Testing statistics by country 1,729 1,729
See also 279 279
References 188 188
Further reading 1,971 1,971
External links 461 461
Total 185,121 185,121

This article was the subject of a Wiki Education Foundation-supported course assignment, between 3 April 2020 and 10 June 2020. Further details are available on the course page. Student editor(s): Elisawulfsberg (article contribs).

Update testing data for spain

This edit request has been answered. Set the |answered= or |ans= parameter to no to reactivate your request.

The last data stated on the table is from 8th september, but it does exist more update information on this webpage, under the name "Pruebas de laboratorio", which is a PDF file with the following information:

Updated the 17th september: - Total PCR: 8,582,722 - Fast Antibody test: 2,351,698 - Other Antibody: 886,085

Which makes a total of: 11,820,505

It would be great if someone could update this info.

--Viferico (talk) 12:37, 25 September 2020 (UTC)

 Already done -ink&fables «talk» 03:46, 19 October 2020 (UTC)

Sensitivity and Specificity

(Minor note: This section in the article currently starts with "Accuracy is measured in terms of specificity and selectivity". Nowhere else in the article does the word "selectivity" appear again.. I assume this is an error, and it should actually read "specificity and sensitivity".) — Preceding unsigned comment added by 136.52.126.31 (talk) 05:50, 14 November 2020 (UTC)

The article doesn't actually say any Covid-19 test's false negative and false positive rates (sensitivity and specificity) despite these being a test's most important features. It just talks about hypothetical rates and the Bayes's Rule problem of getting the posterior probability right.

Googling, it's very hard to find these numbers, despite their importance. Here is some material that might go in.

Fast, low-cost testing is essential for averting a second wave of Covid-19 by MENACHEM FROMER, PAUL VARGHESE, and ROBERT M. CALIFFSEPTEMBER 23, 2020 notes that Abbot Labs's 5-minute test has a 1.5% false positive rate (a 98.5% "specificity").

This is crucial information for the public. If a university is using that test, with its 1.5% false positive rate, or a similar one (and that is a reputable test from a big old respectable company), and is putting 1.5% of its students in quarantine as a result, telling them they have covid, but don't explain test error, students conclude that covid-19 is a harmless infection with no symptoms and no harm, that even precautions such as not coughing on your grandmother are unimportant, and that they will be immune since they had covid already. editeur24 (talk) 14:36, 3 October 2020 (UTC)


Is the sensitivity and specificity section correct? From the "90% specific" example, the sensitivity and specificity article, and the references, it looks like 95% specificity means 95% of the 95 negatives are correctly identified, and for a PPV of 50% that would be 4.75% each of false and true positives from 100 tests, and sensitivity of 95% (or have I misunderstood?) The mention of "coin toss" should be removed, that would be expected to produce 50% positive. According to the source, the percentages after retesting are for 95% specificity, but 90% sensitivity for both tests (also that this is based on them being orthogonal, not just repeating the same test). Peter James (talk) 21:40, 13 October 2020 (UTC)

“Even relatively high sensitivity rates can produce high rates of false negatives in populations with low incidence rates.” from the sensitivity example seems incorrect. I believe that should read: “... with high incidence rates.” The higher the incidence, the more false negatives for a fixed sensitivity. Also, the statement misuses the term “rates of false negatives.” The rate would not change with population incidence. I believe it should read: “... high numbers of false negatives...” Would somebody with the ability to edit this please verify and change this sentence?

Semi-protected edit request on 11 October 2020

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This is regarding the Testing methods for COVID-19 that have been used widely. Also more information regarding the persistence of antibodies providing "immunity passports" to the recovered COVID-19 patients. Asiyazaidi (talk) 19:51, 11 October 2020 (UTC)

 Not done: it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a reliable source if appropriate. -ink&fables «talk» 03:00, 19 October 2020 (UTC)

Semi-protected edit request on 25 October 2020

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The value for the number of tested cases in the Netherlands in table "COVID-19 testing statistics by country" need to be increased by 359,833.

Source: "Epidemiologische situatie COVID-19 in Nederland" (PDF). Rijksinstituut voor Volksgezondheid en Milieu (in Dutch). 2 June 2020. Retrieved 25 October 2020.

Explanation: The number of tests (cases) done in the Netherlands currently in the "COVID-19 testing statistics by country" table are from the 1st of June onwards and is hence not complete. From the report on the 2nd of June (see link), the number of tests (cases) between the 9th of March until the 1st of June (when adding the numbers on page 19) were 359,833 and should be added to the current value.

The Source given is from the government agency which keeps track of the number of tests.

123reks4 (talk) 16:01, 2 November 2020 (UTC)

 Done BJackJS talk 18:05, 4 December 2020 (UTC)

"External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for false positive results."

The study below addresses the problem of false positives on RTPCR test; perhaps something of the above should be reported in this article.

"External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for false positive results."
zenodo.org/record/4298004
cormandrostenreview.com

--5.170.117.113 (talk) 00:13, 5 December 2020 (UTC)

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