Misplaced Pages

This is the current revision of this page, as edited by Zashaw (talk | contribs) at 10:16, 16 October 2022 ("arise" is not a noun). The present address (URL) is a permanent link to this version.

This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these messages) This article is an orphan, as no other articles link to it. Please introduce links to this page from related articles; try the Find link tool for suggestions. (December 2021) This article relies excessively on references to primary sources. Please improve this article by adding secondary or tertiary sources. Find sources: "Mu-gpT-DE RNA motif" – news · newspapers · books · scholar · JSTOR (November 2021) (Learn how and when to remove this message) (Learn how and when to remove this message)

Mu-gpT-DE
Consensus secondary structure and sequence conservation of Mu-gpT-DE RNA
Identifiers
Symbol	Mu-gpT-DE
Rfam	RF03012
Other data
RNA type	Gene; sRNA
SO	SO:0001263
PDB structures	PDBe

The Mu-like gpT Downstream Element RNA motif (Mu-gpT-DE RNA motif) is a conserved RNA structure that was discovered by bioinformatics. The Mu-gpT-DE motif is only found in metagenomic sequences arising from unknown organisms.

Mu-gpT-DE RNAs usually occur downstream of genes whose protein products are similar to gpT. gpT is a protein subunit of the phage head of phages similar to Bacteriophage Mu. This and other observations suggest that Mu-gpT-DE RNAs are found in phages and prophages. Some Mu-gpT-DE RNAs contain a stem that overlaps the Shine-Dalgarno sequence of the downstream gene, which could suggest a cis-regulatory function. However, this phenomenon could also arise if Mu-gpT-DE RNAs are part of a tightly packed genome, as is common with phages. Thus, Mu-gpT-DE RNAs might function as small RNAs.

References

1. Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.

• Non-coding RNA