Misplaced Pages:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox

This is an old revision of this page, as edited by Beetstra (talk | contribs) at 13:44, 10 January 2012 (Saving copy of the {{drugbox}} taken from revid 456619379 of page Tolvaptan for the Chem/Drugbox validation project (updated: 'CAS_number').). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 13:44, 10 January 2012 by Beetstra (talk | contribs) (Saving copy of the {{drugbox}} taken from revid 456619379 of page Tolvaptan for the Chem/Drugbox validation project (updated: 'CAS_number').)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)

This page contains a copy of the infobox ({{drugbox}}) taken from revid 456619379 of page Tolvaptan with values updated to verified values.

WikiProject Chemicals/Chembox validation/VerifiedDataSandbox
Clinical data

Other names	N-{4-undeca-8,10,12-triene-2-carbonyl]-3-methyl-phenyl}-2-methyl-benzamide
AHFS/Drugs.com	Monograph
MedlinePlus	a609033
License data	US FDA: Tolvaptan
Routes of administration	Oral
ATC code	C03XA01 (WHO)
Legal status
Legal status	US: ℞-only
Pharmacokinetic data
Bioavailability	Unknown (40% absorbed)
Protein binding	99%
Metabolism	Hepatic (CYP3A4-mediated)
Elimination half-life	12 hours (terminal)
Identifiers
IUPAC name N-(4-{carbonyl}-3-methylphenyl)-2-methylbenzamide
PubChem CID	216237
ChemSpider	187438
UNII	21G72T1950
ChEMBL	ChEMBL344159
Chemical and physical data
Formula	C₂₆H₂₅ClN₂O₃
Molar mass	448.941 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES O=C(c1ccccc1C)Nc2ccc(c(c2)C)C(=O)N4c3ccc(Cl)cc3C(O)CCC4
InChI InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31) Key:GYHCTFXIZSNGJT-UHFFFAOYSA-N
(what is this?) (verify)

WHO International Working Group for Drug Statistics Methodology (August 27, 2008). "ATC/DDD Classification (FINAL): New ATC 5th level codes". WHO Collaborating Centre for Drug Statistics Methodology. Retrieved 2008-09-05.
Shoaf S, Elizari M, Wang Z; et al. (2005). "Tolvaptan administration does not affect steady state amiodarone concentrations in patients with cardiac arrhythmias". J Cardiovasc Pharmacol Ther. 10 (3): 165–71. doi:10.1177/107424840501000304. PMID 16211205. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)