Misplaced Pages

This is the current revision of this page, as edited by Ozzie10aaaa (talk | contribs) at 15:06, 16 March 2023 (Cleaned up using AutoEd). The present address (URL) is a permanent link to this version.

Albaconazole

Clinical data
ATC code	none
Identifiers
IUPAC name 7-Chloro-3-quinazolin-4-one
CAS Number	187949-02-6
PubChem CID	208952
ChemSpider	181045
UNII	YDW24Y8IAB
KEGG	D09702
ChEMBL	ChEMBL298817
CompTox Dashboard (EPA)	DTXSID3058244
ECHA InfoCard	100.170.829
Chemical and physical data
Formula	C20H16ClF2N5O2
Molar mass	431.83 g·mol
3D model (JSmol)	Interactive image
SMILES Fc1ccc(c(F)c1)(O)((N3\C=N/c2cc(Cl)ccc2C3=O)C)Cn4ncnc4
InChI InChI=1S/C20H16ClF2N5O2/c1-12(28-11-25-18-6-13(21)2-4-15(18)19(28)29)20(30,8-27-10-24-9-26-27)16-5-3-14(22)7-17(16)23/h2-7,9-12,30H,8H2,1H3/t12-,20-/m1/s1 Key:UHIXWHUVLCAJQL-MPBGBICISA-N
(verify)

Albaconazole (development code UR-9825) is an experimental triazole antifungal. It has potential broad-spectrum activity. The drug blocks a number of CYP450 liver enzymes.

It has also been studied as an antiprotozoal agent.

References

1. "Albaconazole". Adis Insight. Springer Nature Switzerland AG.
2. Guedes PM, Urbina JA, de Lana M, Afonso LC, Veloso VM, Tafuri WL, et al. (November 2004). "Activity of the new triazole derivative albaconazole against Trypanosoma (Schizotrypanum) cruzi in dog hosts". Antimicrobial Agents and Chemotherapy. 48 (11): 4286–92. doi:10.1128/AAC.48.11.4286-4292.2004. PMC 525424. PMID 15504854.

This antiinfective drug article is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• Drugs not assigned an ATC code
• Chloroarenes
• Fluoroarenes
• Lactams
• Lanosterol 14α-demethylase inhibitors
• Phenylethanolamines
• Quinazolines
• Tertiary alcohols
• Triazole antifungals
• Antiinfective agent stubs