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5-Hydroxyisourate

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5-Hydroxyisourate
Names
IUPAC name 5-hydroxy-3,7-dihydropurine-2,6,8-trione
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
KEGG
MeSH 5-Hydroxyisourate
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C5H4N4O4/c10-2-5(13)1(6-3(11)8-2)7-4(12)9-5/h13H,(H3,6,7,8,9,10,11,12)Key: LTQYPAVLAYVKTK-UHFFFAOYSA-N
  • InChI=1/C5H4N4O4/c10-2-5(13)1(6-3(11)8-2)7-4(12)9-5/h13H,(H3,6,7,8,9,10,11,12)Key: LTQYPAVLAYVKTK-UHFFFAOYAS
SMILES
  • C12=NC(=O)NC1(C(=O)NC(=O)N2)O
  • O=C1NC(=O)N/C2=N/C(=O)NC12O
Properties
Chemical formula C5H4N4O4
Molar mass 184.11 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

5-Hydroxyisourate is an organic compound that is produced by the oxidation of uric acid. The conversion is a major pathway in the antioxidant properties of ureate. The conversion is catalysed by urate oxidase.

References

  1. Perry A. Frey,Dexter B. Northrop (1999). Enzymatic mechanisms. IOS Press. ISBN 978-9051994322.
  2. Richard B. Silverman (2002). The organic chemistry of enzyme-catalyzed reactions. Academic Press. ISBN 978-0-12-643731-7.
  3. Fetzner, Susanne; Steiner, Roberto A. (2010). "Cofactor-independent oxidases and oxygenases". Applied Microbiology and Biotechnology. 86 (3): 791–804. doi:10.1007/s00253-010-2455-0. PMID 20157809. S2CID 25377247.

See also

Nucleotide metabolic intermediates
purine
metabolism
anabolism
R5PIMP:
IMPAMP:Adenylosuccinate
IMPGMP:Xanthosine monophosphate
catabolism
pyrimidine
metabolism
anabolism
catabolism
uracil:
thymine:



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