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Joseph Schlessinger

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Joseph Schlessinger, Ph.D. is Chair of the Pharmacology Department at Yale University in New Haven, Connecticut. His area of research is Tyrosine phosphorylation which potentially plays a role in the treatment of several different types of cancer.

Education

Joseph Schlessinger has been the William H. Prusoff Professor and Chairman of the Department of Pharmacology at Yale University School of Medicine since 2001. According to his website, prior to coming to Yale, Joseph Schlessinger was the Director of the Skirball Institute for Biomolecular Medicine at New York University (NYU) Medical Center from 1998–2001 and the Milton and Helen Kimmelman Professor and Chairman of the Department of Pharmacology at NYU Medical School from 1990–2001. He was a member of the faculty of the Weizmann Institute from 1978–1991.

Publications

According to PubMed, Joseph Schlessinger has authored over 400 scientific review articles and original publications in the area of pharmacology.

Personal life

Joseph Schlessinger is married to Irit Lax who he appointed as an assistant professor in his Department at shortly after becoming chairman. It is unclear what degree she holds or the exact focus of research, but PubMed shows that she and Joseph Schlessinger co-authored approximately 130 publications together.

Sunitinib Development Controversy

Joseph Schlessinger claims to have come up with the idea of combining an antibody with a chemotherapy agent and founded the drug company Sugen (which was eventually absorbed by Sanofi Aventis and then by ImClone) with the idea of developing this idea. Joseph Schlessinger's colleagues at the Weizmann Institute in Isreal claimed to have come up with this concept first and the case was taken to a district court in the United States. Joseph Schlessinger gave testimony in court that stated the mechamism of the drug was his idea alone. In a Money Magazine article Judge Naomi Reice Buchwald all but accused Joseph Schlessinger of purging himself. Specifically, Judge Buchwald dismissed Joseph Schlessinger's testimony as "'not credible,' 'contorted,' 'incredible' and 'wholly unsubstantiated by any contemporaneous records.'" The verdict of this case went against Joseph Schlessinger who has not made any written response to these allegations. This case was best remembered as the stock collapse that helped land founder Sam Waksal and Martha Stewart in jail.

Yale University

Other

References

  1. Schlessinger Lab: Biography
  2. Schlessinger Lab: Biography
  3. Bruised ImClone takes another hit
  4. ImClone's next headache: The biotech appears likely to lose a patent trial involving Erbitux, its lucrative cancer drug and sole product.
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