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Talk:Huntington's disease/to do

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< Talk:Huntington's disease

This is an old revision of this page, as edited by Leevanjackson (talk | contribs) at 03:04, 1 April 2008 (organisd and added couple of ideas). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

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from peer review

  • The "Genetics" section mentions that repeat number becomes unstable after 35 repeats and causes disease after 40. It should either be briefly explained why the DNA replication machinery has difficulty with repetitive sequences, or at least wikilink to DNA replication so readers can learn about it there.
  • The "Epidemiology" section could use some expansion if the data is available. Is it more prevalent in certain populations or ethnic groups? The prevalence statement also needs a citation,
  • weasel words in the ethics section.

from elsewhere including discussion

  • images
    • graphs of age of onset vs distribution of CAG repeats
    • maybe the huntingtin molecule - (possibly as main image)
    • image of areas of brain affected
    • Epidemiology global map of prevalence
  • history section as prose?