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Sulfadiazine

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Revision as of 01:35, 20 January 2011 by CheMoBot (talk | contribs) (Updating {{drugbox}} (changes to verified fields - added verified revid - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per [[Misplaced Pages:WikiProject Chemicals/Chembox validation|Chem/Drugbox valid)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Sulfadiazine
Clinical data
Pregnancy
category
  • ?
Routes of
administration
Cream
ATC code
Legal status
Legal status
  • Approved Drug
Pharmacokinetic data
Bioavailability?
Metabolism?
Elimination half-life?
Excretion?
Identifiers
IUPAC name
  • 4-amino-N-pyrimidin- 2-yl-benzenesulfonamide
CAS Number
PubChem CID
DrugBank
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.000.623 Edit this at Wikidata
Chemical and physical data
FormulaC10H10N4O2S
Molar mass250.278 g/mol g·mol
  (what is this?)  (verify)

Sulfadiazine is a sulfonamide antibiotic.

Uses

It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.

Side effects

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand names

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also

External links


Antibacterials that inhibit nucleic acid (J01E, J01M)
Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor
Sulfonamides
(DHPS inhibitor)
Short-acting
Intermediate-acting
Long-acting
Other/ungrouped
Combinations
Other DHPS inhibitors
Quinolones
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation
Fluoroquinolones
2nd generation
3rd generation
4th generation
Veterinary
Newer non-fluorinated
Related (DG)
Anaerobic DNA
inhibitors
Nitroimidazole derivatives
RNA synthesis
Rifamycins/
RNA polymerase
Lipiarmycins
Antiparasiticsantiprotozoal agentsChromalveolata antiparasitics (P01)
Alveo-
late
Apicom-
plexa
Conoidasida/
(Coccidiostats)
Cryptosporidiosis
Isosporiasis
Toxoplasmosis
Aconoidasida
Malaria
Individual
agents
Hemozoin
inhibitors
Aminoquinolines
4-Methanolquinolines
Other
Antifolates
DHFR inhibitors
Sulfonamides
Co-formulation
Sesquiterpene
lactones
Other
Combi-
nations
Fixed-dose (co-formulated) ACTs
Other combinations
(not co-formulated)
  • artesunate/mefloquine
  • artesunate/SP
  • quinine/clindamycin
  • quinine/doxycycline
  • quinine/tetracycline
Babesiosis
Cilio-
phora
Stramen-
opile


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