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n-Propyl azide

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n-Propyl azide
Names
IUPAC name 1-Azidopropane
Identifiers
CAS Number
3D model (JSmol)
CompTox Dashboard (EPA)
SMILES
  • ==NCCC
Properties
Chemical formula C3H7N3
Molar mass 85.110 g·mol
Hazards
Occupational safety and health (OHS/OSH):
Main hazards Harmful, Explosive
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

n-Propyl azide is a covalent molecule related to hydrazoic acid and other alkyl azides.

n-Propyl azide has been used in the laboratory synthesis of pharmaceutical drug candidates.

References

  1. Stefan Bräse (Editor), Klaus Banert (Co-Editor); Organic Azides: Syntheses and Applications; 2010 John Wiley and Sons; ISBN 978-0-470-51998-1
  2. Helmut Haning; et al. (2005). "Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitors". Bioorganic & Medicinal Chemistry Letters. 15 (17): 3900–3907. {{cite journal}}: Explicit use of et al. in: |author= (help)
  3. Michael H. Parker; et al. (2002). "Synthesis of (-)-5,8-Dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: An Inhibitor of β-Amyloid1-42 Aggregation". Bioorganic & Medicinal Chemistry. 10 (11): 3565–3569. {{cite journal}}: Explicit use of et al. in: |author= (help)

Further reading

  • Edward J. Kaufmann, Richard C. Thompson (1977). "Reduction of organic azides by chromium(II) in aqueous solution". JACS. 99 (6): 1824–1830. doi:10.1021/ja00448a025.


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