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3,3'-Diiodothyronine

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3,3'-Diiodothyronine
Names
IUPAC name 2-Amino-3-propanoic acid
Other names O-(4-Hydroxy-3-iodophenyl)-3-iodotyrosine
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
MeSH 3,3'-diiodothyronine
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)Key: CPCJBZABTUOGNM-UHFFFAOYSA-N
  • InChI=1/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)Key: CPCJBZABTUOGNM-UHFFFAOYAW
SMILES
  • NC(C(O)=O)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C=C1
  • O=C(O)C(N)Cc2ccc(Oc1cc(I)c(O)cc1)c(I)c2
Properties
Chemical formula C15H13I2NO4
Molar mass 525.077
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

3,3'-Diiodothyronine is a metabolite of thyroid hormone.

It is formed from the breakdown of tri-iodothyronine (T3).

Levels can be affected in certain disease states.

Reactions

Synthesis

References

  1. Pinna G, Hiedra L, Meinhold H; et al. (1998). "3,3'-Diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors and of healthy subjects during acute stress". J. Clin. Endocrinol. Metab. 83 (9): 3071–7. doi:10.1210/jc.83.9.3071. PMID 9745405. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
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Thyroid hormone metabolic intermediates
Tyrosine / iodotyrosine
Thyronine / iodothyronine
Thyronamine / iodothyronamine
Iodothyroacetate / iodothyroacetic acid
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