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Orotidine 5'-monophosphate

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Orotidine 5'-monophosphate
Names
IUPAC name 3-​-2,6-dioxo-pyrimidine-4-carboxylic acid
Other names Orotidylic acid,
OMP
Identifiers
CAS Number
3D model (JSmol)
MeSH Orotidine+5'-monophosphate
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • C1=C(N(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O)C(=O)O
Properties
Chemical formula C10H13N2O11P
Molar mass 368.191 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase

In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.

Nucleotide metabolic intermediates
purine
metabolism
anabolism
R5PIMP:
IMPAMP:Adenylosuccinate
IMPGMP:Xanthosine monophosphate
catabolism
pyrimidine
metabolism
anabolism
catabolism
uracil:
thymine:


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