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Punicalagin alpha

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Punicalagin alpha
Chemical structure of punicalagin alpha
Chemical structure of punicalagin alpha
Names
Other names 1-alpha-O-galloylpunicalagin
Identifiers
Properties
Chemical formula C55H32O34
Molar mass 1236.82 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

Punicalagin alpha is a punicalagin, a type of hydrolysable tannins.

A study in Taiwan showed that punicalagin alpha (1-alpha-O-galloylpunicalagin) induced nitric oxide production in a dose-dependent manner in endothelial cells as well as inhibited ERK, JNK and Akt, all of which play roles in cancer growth, so their inhibition points to punicalagins' potential as strong cancer suppressors.

References

  1. http://www.ncbi.nlm.nih.gov/pubmed/18435486 "Tannin 1-alpha-O-galloylpunicalagin induces the calcium-dependent activation of endothelial nitric-oxide synthase via the phosphatidylinositol 3-kinase/Akt pathway in endothelial cells."
Types of ellagitannins
Moieties
Lactones
Monomers
C-glycosidic ellagitannins
Dehydroellagitannins (molecules with
dehydrohexahydroxydiphenic acid (DHHDP)
Transformed ellagitannins
molecules with chebulic acid
molecules with Elaeocarpusinic acid
Oligomers
Dimers
Agrimoniin
Cornusiin E (dimer of tellimagrandin II)
Lambertianin A and B
Nobotanin B
Roburin A, B, C and D
Sanguiin H-6
Trimers
Lambertianin C
Raspberry ellagitannin
Tetramers
Lambertianin D
Nobotanin S
Pentamer
Melastoflorin A
Other

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