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Revision as of 07:33, 15 August 2011 by CheMoBot (talk | contribs) (Updating {{chembox}} (no changed fields - added verified revid - updated 'ChemSpiderID_Ref', 'DrugBank_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEBI_Ref') per [[Misplaced Pages:WikiProject Chemicals/Chembox validati)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) | This article is an orphan, as no other articles link to it. Please introduce links to this page from related articles; try the Find link tool for suggestions. (April 2010) |
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| Names | |
|---|---|
| IUPAC name azane; 2-methylpyridine; platinum(2+); dichloride | |
| Identifiers | |
| CAS Number | |
| 3D model (JSmol) | |
| ECHA InfoCard | 100.205.233 
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| PubChem CID | |
| CompTox Dashboard (EPA) | |
SMILES
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| Properties | |
| Chemical formula | C6H10Cl2N2Pt |
| Molar mass | 376.14 g·mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
 Y verify (what is ?)
Infobox references
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Picoplatin is a cytotoxic platinum compound in clinical development by Poniard Pharmaceuticals (previously NeoRx) for the treatment of patients with solid tumors.
In Phase I and Phase II clinical trials, picoplatin demonstrated activity in a variety of solid tumors, including lung, ovarian, colorectal and hormone-refractory prostate cancer. However, in Phase III trials, picoplatin failed to hit its primary endpoint for advanced small cell lung cancer. Hopes are now pinned on its use for metastatic colorectal cancer.
References
- The status of platinum anticancer drugs in the clinic and in clinical trials Dalton Transactions
- Picoplatin Clinical Results, Poniard Pharmaceuticals
- Poniard shares crash on Phase III picoplatin failure, fiercebiotech.com, November 16, 2009
- http://www.genengnews.com/specialreports/sritem.aspx?oid=69418732 Nov 2009
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