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Benzethidine

Clinical data
ATC code	none
Legal status
Legal status	CA: Schedule I UK: Class A US: Schedule I
Identifiers
IUPAC name ethyl 1-- 4-phenylpiperidine- 4-carboxylate
CAS Number	3691-78-9
PubChem CID	62516
DrugBank	DB01518
ChemSpider	56290
UNII	X0I74BAR02
CompTox Dashboard (EPA)	DTXSID50190389
Chemical and physical data
Formula	C23H29NO3
Molar mass	367.481 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES O=C(OCC)C3(c1ccccc1)CCN(CCOCc2ccccc2)CC3
InChI InChI=1S/C23H29NO3/c1-2-27-22(25)23(21-11-7-4-8-12-21)13-15-24(16-14-23)17-18-26-19-20-9-5-3-6-10-20/h3-12H,2,13-19H2,1H3 Key:UVTBZAWTRVBTMK-UHFFFAOYSA-N
(verify)

Benzethidine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine, or Demerol).

Benzethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.

References

1. Maul C, Buschmann H, Sundermann B. Opioids: 3.3 Synthetic Opioids. Analgesics 2005; 159-169. ISBN 9783527304035
2. Cahal DA, Dare JG, Keith D. A Sequential Trial of Analgesics in Labour. International Journal of Obstetrics and Gynaecology 1961; 68(1): 88–93.

UNODC Bulletin on Narcotics 1961

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