Thyronamine - Misplaced Pages

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Thyronamine
Identifiers


CAS Number	500-78-7
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL201896
ChemSpider	2340781
MeSH	thyronamine
PubChem CID	3083601
CompTox Dashboard (EPA)	DTXSID60198174
InChI InChI=1S/C14H15NO2/c15-10-9-11-1-5-13(6-2-11)17-14-7-3-12(16)4-8-14/h1-8,16H,9-10,15H2Key: OVUVNKDANCKDCK-UHFFFAOYSA-N InChI=1/C14H15NO2/c15-10-9-11-1-5-13(6-2-11)17-14-7-3-12(16)4-8-14/h1-8,16H,9-10,15H2Key: OVUVNKDANCKDCK-UHFFFAOYAP
SMILES O(c1ccc(cc1)CCN)c2ccc(O)cc2
Properties
Chemical formula	C₁₄H₁₅NO₂
Molar mass	229.274 g mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references

Chemical compound

Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).

Types

The group includes:

Thyronamine (T0AM)
3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), a G protein-coupled receptor located in the cell membrane.
3,5-Diiodothyronamine (T2AM)
3,5,3'-Triiodothyronamine (T3AM)

v t e Thyroid hormone metabolic intermediates
Tyrosine / iodotyrosine	3-Iodotyrosine Diiodotyrosine
Thyronine / iodothyronine	3'-Monoiodothyronine 3,3'-Diiodothyronine 3,5-Diiodothyronine 3,3',5-Triiodothyronine (T₃) 3,3',5'-Triiodothyronine (Reverse T₃) 3,5,3',5'-Tetraiodothyronine (Thyroxine, T₄)
Thyronamine / iodothyronamine	3-Iodothyronamine 3,3',5-Triiodothyronamine
Iodothyroacetate / iodothyroacetic acid	Triiodothyroacetate (TRIAC)

Types

See also