Leonurine - Misplaced Pages

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Leonurine
Names

IUPAC name 4-Hydroxy-3,5-dimethoxybenzoic acid 4-guanidinobutyl ester
Identifiers
CAS Number	24697-74-3
3D model (JSmol)	Interactive image
ChemSpider	141828
ECHA InfoCard	100.208.686
KEGG	C16985
PubChem CID	161464
CompTox Dashboard (EPA)	DTXSID70179434
InChI InChI=1S/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)Key: WNGSUWLDMZFYNZ-UHFFFAOYSA-N InChI=1/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)Key: WNGSUWLDMZFYNZ-UHFFFAOYAI
SMILES O=C(OCCCC/N=C(\N)N)c1cc(OC)c(O)c(OC)c1
Properties
Chemical formula	C₁₄H₂₁N₃O₅
Molar mass	311.338 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references

Chemical compound

Leonurine is one of the chemical constituents of the South African plant Leonotis leonurus. It is a mildly psychoactive alkaloid found in species Leonotis nepetifolia, Leonotis artemisia as well as other plants of family Lamiaceae. Leonurine is easily extracted into water, as well as from the essential oil of Leonurus sibiricus.

Traditional uses

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Primary uses include treatment of:

Respiratory tract infections caused by Streptococcus pneumoniae and group A β-hemolytic streptococci.
Otitis media due to S. pneumoniae, Hemophilus influenzae, Moraxella catarrhalis, staphylococci, streptococci, and N. catarrhalis.
GU infections (including acute prostatitis) due to Escherichia coli, Proteus mirabilis or Klebsiella species.
Bone infections caused by P. mirabilis or staphylococci.
Skin and skin structure infections due to staphylococci and streptococci.

"The Leonurine and its preparation". An Hui New Star Pharmaceutical Development Co. 2008. Retrieved 2008-08-28.