This is an old revision of this page, as edited by Beetstra (talk | contribs) at 11:07, 16 February 2012 (Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'UNII').). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
Revision as of 11:07, 16 February 2012 by Beetstra (talk | contribs) (Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'UNII').)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff){{Chembox | ImageFile = Bilastine.svg | ImageSize = 200px | IUPACName = 2--1-piperidinyl}ethyl)phenyl]-2-methylpropanoic acid | OtherNames = | Section1 = ! colspan=2 style="background: #f8eaba; text-align: center;" |Identifiers
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CAS Number|
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3D model (JSmol)|
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| ECHA InfoCard
| 100.260.016 
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PubChem CID|
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| UNII
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CompTox Dashboard (EPA)|
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| colspan="2" |
InChI- InChI=1S/C28H37N3O3/c1-4-34-20-19-31-25-8-6-5-7-24(25)29-26(31)22-14-17-30(18-15-22)16-13-21-9-11-23(12-10-21)28(2,3)27(32)33/h5-12,22H,4,13-20H2,1-3H3,(H,32,33)Key: ACCMWZWAEFYUGZ-UHFFFAOYSA-N
- InChI=1/C28H37N3O3/c1-4-34-20-19-31-25-8-6-5-7-24(25)29-26(31)22-14-17-30(18-15-22)16-13-21-9-11-23(12-10-21)28(2,3)27(32)33/h5-12,22H,4,13-20H2,1-3H3,(H,32,33)Key: ACCMWZWAEFYUGZ-UHFFFAOYAW
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SMILES- O=C(O)C(c1ccc(cc1)CCN4CCC(c2nc3ccccc3n2CCOCC)CC4)(C)C
|- | Section2 = ! colspan=2 style="background: #f8eaba; text-align: center;" |Properties
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Chemical formula| C28H37N3O3
|- | Molar mass
| 463.622 g·mol
|- | Section3 = | Section5 = }}
Bilastine (tradename: Bilaxten) is an antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives). It was approved for use in the European Union in 2010.
It exerts its effect as a selective histamine H1 receptor antagonist.
References
- Annual Reports in Medicinal Chemistry. 46: 449–451.
{{cite journal}}: Missing or empty|title=(help) - Corcóstegui, R; Labeaga, L; Innerárity, A; Berisa, A; Orjales, A (2005). "Preclinical pharmacology of bilastine, a new selective histamine H1 receptor antagonist: Receptor selectivity and in vitro antihistaminic activity". Drugs in R&D. 6 (6): 371–84. PMID 16274260.
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